Product Name
SHFM1, cDNA Clone
Popular Item
Full Product Name
SHFM1 cDNA Clone
Product Gene Name
SHFM1 cdna clone
[Similar Products]
Research Use Only
For Research Use Only. Not for use in diagnostic procedures.
Sequence
atgtcagaga aaaagcagcc ggtagactta ggtctgttag aggaagacga cgagtttgaa gagttccctg ccgaagactg ggctggctta gatgaagatg aagatgcaca tgtctgggag gataattggg atgatgacaa tgtagaggat gacttctcta atcagttacg agctgaacta gagaaacatg gttataagat ggagacttca tag
Clone Sequence Report
Provided with product shipment
ISO Certification
Manufactured in an ISO 13485:2003 and EN ISO 13485:2012 Certified Laboratory.
Other Notes
Small volumes of SHFM1 cdna clone vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
NCBI/Uniprot data below describe general gene information for SHFM1. It may not necessarily be applicable to this product.
NCBI Accession #
BC032782
[Other Products]
UniProt Secondary Accession #
Q13437; Q61067[Other Products]
UniProt Related Accession #
P60896[Other Products]
Molecular Weight
8,278 Da
NCBI Official Full Name
Homo sapiens split hand/foot malformation (ectrodactyly) type 1, mRNA
NCBI Official Synonym Full Names
split hand/foot malformation (ectrodactyly) type 1
NCBI Official Symbol
SHFM1??[Similar Products]
NCBI Official Synonym Symbols
ECD; DSS1; SEM1; SHFD1; SHSF1; Shfdg1
??[Similar Products]
NCBI Protein Information
26S proteasome complex subunit DSS1
UniProt Protein Name
26S proteasome complex subunit DSS1
UniProt Synonym Protein Names
Deleted in split hand/split foot protein 1; Split hand/foot deleted protein 1; Split hand/foot malformation type 1 protein
Protein Family
26S proteasome complex
UniProt Gene Name
SHFM1??[Similar Products]
UniProt Synonym Gene Names
DSS1; SHFDG1??[Similar Products]
UniProt Entry Name
DSS1_HUMAN
NCBI Summary for SHFM1
The product of this gene has been localized within the split hand/split foot malformation locus SHFM1 at chromosome 7. It has been proposed to be a candidate gene for the autosomal dominant form of the heterogeneous limb developmental disorder split hand/split foot malformation type 1. In addition, it has been shown to directly interact with BRCA2. It also may play a role in the completion of the cell cycle. [provided by RefSeq, Jul 2008]
UniProt Comments for SHFM1
SHFM1: Subunit of the 26S proteasome which plays a role in ubiquitin-dependent proteolysis. Belongs to the DSS1/SEM1 family.
Protein type: Protease; DNA repair, damage; Proteasome complex
Chromosomal Location of Human Ortholog: 7q21.3
Cellular Component: integrator complex; proteasome complex
Molecular Function: protein binding
Biological Process: double-strand break repair via homologous recombination; proteolysis
Disease: Split-hand/foot Malformation 1
Research Articles on SHFM1
1. three phenotypic subregions within the SHFM1 locus link both size and genomic position of the chromosomal aberrations to the clinical variability seen in SHFM1 patients
Precautions
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Disclaimer
While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.
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