Product Name
ANKS6, Blocking Peptide
Full Product Name
ANKS6 Antibody (Center) Blocking peptide
Product Synonym Names
Ankyrin repeat and SAM domain-containing protein 6; Ankyrin repeat domain-containing protein 14; SamCystin; Sterile alpha motif domain-containing protein 6; SAM domain-containing protein 6; ANKS6; ANKRD14; PKDR1; SAMD6
Product Gene Name
ANKS6 blocking peptide
[Similar Products]
Product Synonym Gene Name
ANKRD14; PKDR1; SAMD6[Similar Products]
Antibody/Peptide Pairs
ANKS6 peptide (MBS9220342) is used for blocking the activity of ANKS6 antibody (MBS9203500)
Research Use Only
For Research Use Only. Not for use in diagnostic procedures.
3D Structure
ModBase 3D Structure for Q68DC2
Specificity
The synthetic peptide sequence used to generate the antibody was selected from the Center region of ANKS6. A 10 to 100 fold molar excess to antibody is recommended. Precise conditions should be optimized for a particular assay.
Form/Format
Synthetic peptide was lyophilized with 100% acetonitrile and is supplied as a powder. Reconstitute with 0.1 ml DI water for a final concentration of 1 mg/ml.
Cellular Location
Cell projection, cilium. Cytoplasm. Note: Localizes to the proximal region of the primary cilium in the presence of INVS.
Preparation and Storage
Maintain refrigerated at 2-8 degree C for up to 6 months. For long term storage store at -20 degree C.
Other Notes
Small volumes of ANKS6 blocking peptide vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
Related Product Information for
ANKS6 blocking peptide
Required for renal function.
NCBI/Uniprot data below describe general gene information for ANKS6. It may not necessarily be applicable to this product.
NCBI Accession #
Q68DC2.2
[Other Products]
UniProt Primary Accession #
Q68DC2
[Other Products]
UniProt Secondary Accession #
Q5VSL0; Q5VSL2; Q5VSL3; Q5VSL4; Q68DB8; Q6P2R2; Q8N9L6; Q96D62; A0SE62[Other Products]
UniProt Related Accession #
Q68DC2[Other Products]
Molecular Weight
92,347 Da
NCBI Official Full Name
Ankyrin repeat and SAM domain-containing protein 6
NCBI Official Synonym Full Names
ankyrin repeat and sterile alpha motif domain containing 6
NCBI Official Symbol
ANKS6??[Similar Products]
NCBI Official Synonym Symbols
PKDR1; SAMD6; NPHP16; ANKRD14
??[Similar Products]
NCBI Protein Information
ankyrin repeat and SAM domain-containing protein 6
UniProt Protein Name
Ankyrin repeat and SAM domain-containing protein 6
UniProt Synonym Protein Names
Ankyrin repeat domain-containing protein 14; SamCystin; Sterile alpha motif domain-containing protein 6; SAM domain-containing protein 6
Protein Family
Ankyrin repeat and SAM domain-containing protein
UniProt Gene Name
ANKS6??[Similar Products]
UniProt Synonym Gene Names
ANKRD14; PKDR1; SAMD6; SAM domain-containing protein 6??[Similar Products]
UniProt Entry Name
ANKS6_HUMAN
NCBI Summary for ANKS6
This gene encodes a protein containing multiple ankyrin repeats and a SAM domain. It is thought that this protein may localize to the proximal region of the primary cilium, and may play a role in renal and cardiovascular development. Mutations in this gene have been shown to cause a form of nephronophthisis (NPHP16), a chronic tubulo-interstitial nephritis. [provided by RefSeq, Jul 2015]
UniProt Comments for ANKS6
ANKS6: Required for renal function. 3 isoforms of the human protein are produced by alternative splicing.
Chromosomal Location of Human Ortholog: 9q22.33
Disease: Nephronophthisis 16
Research Articles on ANKS6
1. Study finds that ANKS3-SAM polymerizes and ANKS6-SAM can bind to one end of the polymer; study presents crystal structures of both the ANKS3-SAM polymer and the ANKS3-SAM/ANKS6-SAM complex, revealing the molecular details of their association.
Precautions
All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
Disclaimer
While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.
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