Product Name
Amylin (IAPP), Polyclonal Antibody
Full Product Name
Rabbit polyclonal Amylin antibody (HRP)
Product Synonym Names
Amylin antibody (HRP)
Product Gene Name
anti-IAPP antibody
[Similar Products]
Research Use Only
For Research Use Only. Not for use in diagnostic procedures.
Purity/Purification
Purified by Ammonium Sulfate precipitation
Form/Format
Supplied with 0.03% Proclin 300, 50% Glycerol and 0.01M PBS, PH 7.4
Immunogen
Amylin antibody (HRP) was raised in Rabbit using recombinant human Amylin as the immunogen
Preparation and Storage
Store at 4 degree C for short term storage and -20 degree C for long term storage. Avoid repeat freeze/thaw cycles.
Other Notes
Small volumes of anti-IAPP antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
Product Categories/Family for anti-IAPP antibody
Nutrition & Metabolism
Applications Tested/Suitable for anti-IAPP antibody
ELISA (EIA), Immunohistochemistry (IHC), Western Blot (WB)
NCBI/Uniprot data below describe general gene information for IAPP. It may not necessarily be applicable to this product.
NCBI Accession #
AAA35524.1
[Other Products]
UniProt Secondary Accession #
Q0ZD87; Q14598[Other Products]
UniProt Related Accession #
P10997[Other Products]
Molecular Weight
9,806 Da[Similar Products]
NCBI Official Full Name
amylin, partial
NCBI Official Synonym Full Names
islet amyloid polypeptide
NCBI Official Symbol
IAPP??[Similar Products]
NCBI Official Synonym Symbols
DAP; IAP
??[Similar Products]
NCBI Protein Information
islet amyloid polypeptide
UniProt Protein Name
Islet amyloid polypeptide
UniProt Synonym Protein Names
Amylin; Diabetes-associated peptide; DAP; Insulinoma amyloid peptide
Protein Family
Islet amyloid polypeptide
UniProt Gene Name
IAPP??[Similar Products]
UniProt Synonym Gene Names
DAP??[Similar Products]
NCBI Summary for IAPP
This gene encodes a member of the calcitonin family of peptide hormones. This hormone is released from pancreatic beta cells following food intake to regulate blood glucose levels and act as a satiation signal. Human patients with type 1 and advanced type 2 diabetes exhibit reduced levels of the encoded hormone in blood and pancreas. This protein also exhibits a bactericidal, antimicrobial activity. [provided by RefSeq, Jul 2016]
UniProt Comments for IAPP
IAPP: Selectively inhibits insulin-stimulated glucose utilization and glycogen deposition in muscle, while not affecting adipocyte glucose metabolism. Belongs to the calcitonin family.
Protein type: Secreted; Secreted, signal peptide
Chromosomal Location of Human Ortholog: 12p12.1
Cellular Component: extracellular region
Molecular Function: identical protein binding; receptor binding
Biological Process: apoptosis; cell-cell signaling; cellular protein metabolic process; signal transduction
Research Articles on IAPP
1. hA17-29 aggregate toxicity seems to be mediated by RAGE and p75-NGFR receptors
Precautions
All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
Disclaimer
While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.
It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
