Product Name
IFT80, cDNA Clone
Full Product Name
IFT80 cDNA Clone
Product Gene Name
IFT80 cdna clone
[Similar Products]
Research Use Only
For Research Use Only. Not for use in diagnostic procedures.
Sequence
atgagactaa agatatctct tttaaaagaa ccaaagcatc aagaattagt aagctgtgtg ggctggacta ctgctgaaga gctgtattca tgtagtgatg atcaccagat agtgaagtgg aacttgttaa ccagtgaaac aactcaaata gtaaagcttc ctgatgatat ttaccctatt gattttcact ggtttccaaa aagtttgggt gtaaagaaac aaacccaggc agaaagcttt gtcctcacaa gttctgatgg taaatttcat ctgatttcca agttaggaag agtggaaaaa agtgtagaag ctcactgtgg agcagtactt gcaggaagat ggaattatga aggaacagca ttagttacag ttggagaaga tggacaaata aaaatttggt caaagactgg gatgcttaga tcaactttag ctcagcaagg aacaccagtg tattcagtag cgtggggccc tgattcagaa aaggttcttt atacagcagg caagcagcta atcattaaac ctcttcaacc aaatgctaaa gttttgcagt ggaaagctca tgatggcatt attttaaaag tagattggaa ctcggtcaat gatcttattt tatctgctgg tgaagactgt aaatataagg tatgggatag ttacggccgc ccactgtaca attcacaacc tcatgagcat cccattactt cagttgcctg ggctccagat ggagaattat ttgctgttgg atcgtttcat actttacgct tgtgtgataa aactgggtgg tcatatgcat tagaaaaacc caacactggc agcatattta atattgcatg gtctatcgat ggcactcaga ttgctggagc ctgtggaaat ggacatgtcg tttttgcaca tgtggtggaa caacattggg agtggaaaaa ttttcaagta acattaacga aaagaagagc catgcaggtt cgtaatgttc ttaatgatgc agtggattta ctggaattcc gtgatagagt cattaaagca tctttgaact atgcacactt agttgtttca acgtctcttc aatgttacgt gttctccacg aagaactgga acacaccaat tatatttgat ctcaaagaag gaactgttag tttgattctg caggcagaaa gacattttct tcttgtagat ggtagtagta tctatttata ttcatatgaa gggcgcttta tttcatctcc aaaatttcct ggaatgagaa cagatattct gaatgcacag actgtgtctt tgagtaatga taccatagca ataagagaca aagctgatga aaaaataatc ttcctctttg aggcatcaac cggaaagccg ttaggtgatg gaaagtttct ttctcataag aatgaaatct tggaaattgc tctggatcaa aaaggactta ccaatgatag aaaaattgct ttcattgata aaaatagaga tctctgtatc acttctgtga aacgatttgg gaaggaagaa caaattatca agcttggaac aatggtgcat actttggcat ggaacgatac atgcaatatc ctttgtggac ttcaagatac tcgatttata gtgtggtatt accccaatac agtttatgtg gacagagaca ttttgcctaa aacattatat gaaagggatg caagtgaatt tagtaaaaat ccccatattg tgagttttgt tggaaatcaa gtaactatta gaagagctga tggctccctg gttcacatca gcataacacc atatcctgct attctccatg aatatgtaag cagttcaaaa tgggaagatg ctgtgagact ttgtcgcttt gttaaggagc aaaccatgtg ggcttgtcta gctgctatgg cagttgctaa tcgagatatg actactgcag aaatagccta tgcagcaatt ggtgaaattg ataaggttca gtacatcaat tctataaaaa atcttccatc taaagaatca aaaatggccc acatactact gtttagtggg aacatacagg aggctgaaat agtacttctt caggctggcc ttgtttatca agcaatccag atcaatatta atctctacaa ctgggaaagg gcactggaat tggctgtaaa atacaaaaca catgttgata cagttcttgc ttaccgtcaa aagtttttgg agacatttgg taaacaggaa actaataaac gatacttgca ttatgcagaa ggtctccaaa tagattggga gaaaatcaaa gccaaaattg agatggaaat tacaaaagaa agagagcaat catcaagcag ccaatccagc aagagtatag gtttaaagcc ctaa
Clone Sequence Report
Provided with product shipment
ISO Certification
Manufactured in an ISO 13485:2003 and EN ISO 13485:2012 Certified Laboratory.
Other Notes
Small volumes of IFT80 cdna clone vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
NCBI/Uniprot data below describe general gene information for IFT80. It may not necessarily be applicable to this product.
NCBI Accession #
BC113669
[Other Products]
UniProt Secondary Accession #
Q3MJC4; Q86YF4; Q9UIX1; B4E0K1; C9J8I0[Other Products]
UniProt Related Accession #
Q9P2H3[Other Products]
Molecular Weight
123,321 Da
NCBI Official Full Name
Homo sapiens intraflagellar transport 80 homolog (Chlamydomonas), mRNA
NCBI Official Synonym Full Names
intraflagellar transport 80
NCBI Official Symbol
IFT80??[Similar Products]
NCBI Official Synonym Symbols
ATD2; SRTD2; WDR56
??[Similar Products]
NCBI Protein Information
intraflagellar transport protein 80 homolog
UniProt Protein Name
Intraflagellar transport protein 80 homolog
UniProt Synonym Protein Names
WD repeat-containing protein 56
Protein Family
Intraflagellar transport protein
UniProt Gene Name
IFT80??[Similar Products]
UniProt Synonym Gene Names
KIAA1374; WDR56??[Similar Products]
UniProt Entry Name
IFT80_HUMAN
NCBI Summary for IFT80
The protein encoded by this gene is part of the intraflagellar transport complex B and is necessary for the function of motile and sensory cilia. Defects in this gene are a cause of asphyxiating thoracic dystrophy 2 (ATD2). Three transcript variants encoding two different isoforms have been found for this gene.[provided by RefSeq, Jun 2010]
UniProt Comments for IFT80
IFT80: Component of the intraflagellar transport (IFT) complex B, which is essential for the development and maintenance of motile and sensory cilia. Defects in IFT80 are the cause of asphyxiating thoracic dystrophy type 2 (ATD2). An autosomal recessive chondrodysplasia characterized by a severely constricted thoracic cage, short-limbed short stature, and polydactyly. It often leads to death in infancy because of respiratory insufficiency. Retinal degeneration, cystic renal disease and hepatic disease can be present in affected individuals who survive early childhood.
Chromosomal Location of Human Ortholog: 3q25.33
Cellular Component: centrosome; cilium
Biological Process: cilium biogenesis
Disease: Short-rib Thoracic Dysplasia 2 With Or Without Polydactyly
Research Articles on IFT80
1. Mutations in IFT80 can be responsible for a lethal form of short-rib polydactyly and provide the molecular basis for the Jeune-Verma-Naumoff dysplasia spectrum.
Precautions
All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
Disclaimer
While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.
It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
