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IFT80, Polyclonal Antibody

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產(chǎn)品名稱: IFT80, Polyclonal Antibody
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IFT80, Polyclonal Antibody


IFT80, Polyclonal Antibody  的詳細介紹
Product Name

IFT80, Polyclonal Antibody

Full Product Name

IFT80 Antibody; HRP conjugated

Product Synonym Names
Intraflagellar transport protein 80 homolog; WD repeat-containing protein 56; IFT80; KIAA1374; WDR56
Product Gene Name

anti-IFT80 antibody

[Similar Products]
Research Use Only
For Research Use Only. Not for use in diagnostic procedures.
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OMIM
611177
3D Structure
ModBase 3D Structure for Q9P2H3
Clonality
Polyclonal
Isotype
IgG
Host
Rabbit
Species Reactivity
Human
Purity/Purification
>95%,Protein G purified
Form/Format
Liquid
Immunogen
Recombinant human Intraflagellar transport protein 80 homolog protein
Conjugation
HRP
Storage Buffer
Preservative: 0.03% Proclin 300 Constituents: 50% Glycerol, 0.01M PBS, PH 7.4
Preparation and Storage
Shipped at 4 degree C. Upon delivery, aliquot and store at -20 degree C or -80 degree C.
ISO Certification
Manufactured in an ISO 13485:2003 and EN ISO 13485:2012 Certified Laboratory.
Other Notes
Small volumes of anti-IFT80 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
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Related Product Information for
anti-IFT80 antibody
Component of the intraflagellar transport (IFT) complex B, which is essential for the development and maintenance of motile and sensory cilia.
Applications Tested/Suitable for anti-IFT80 antibody
ELISA (EIA)
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NCBI/Uniprot data below describe general gene information for IFT80. It may not necessarily be applicable to this product.
NCBI GI #
298160996
NCBI GeneID
57560
NCBI Accession #
NP_001177170.1 [Other Products]
NCBI GenBank Nucleotide #
NM_001190241.1 [Other Products]
UniProt Primary Accession #
Q9P2H3 [Other Products]
UniProt Secondary Accession #
Q3MJC4; Q86YF4; Q9UIX1; B4E0K1; C9J8I0[Other Products]
UniProt Related Accession #
Q9P2H3[Other Products]
Molecular Weight
123,321 Da
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NCBI Official Full Name
intraflagellar transport protein 80 homolog isoform b
NCBI Official Synonym Full Names
intraflagellar transport 80
NCBI Official Symbol
IFT80??[Similar Products]
NCBI Official Synonym Symbols
ATD2; SRTD2; WDR56
??[Similar Products]
NCBI Protein Information
intraflagellar transport protein 80 homolog
UniProt Protein Name
Intraflagellar transport protein 80 homolog
UniProt Synonym Protein Names
WD repeat-containing protein 56
Protein Family
Intraflagellar transport protein
UniProt Gene Name
IFT80??[Similar Products]
UniProt Synonym Gene Names
KIAA1374; WDR56??[Similar Products]
UniProt Entry Name
IFT80_HUMAN
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NCBI Summary for IFT80
The protein encoded by this gene is part of the intraflagellar transport complex B and is necessary for the function of motile and sensory cilia. Defects in this gene are a cause of asphyxiating thoracic dystrophy 2 (ATD2). Three transcript variants encoding two different isoforms have been found for this gene.[provided by RefSeq, Jun 2010]
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UniProt Comments for IFT80
IFT80: Component of the intraflagellar transport (IFT) complex B, which is essential for the development and maintenance of motile and sensory cilia. Defects in IFT80 are the cause of asphyxiating thoracic dystrophy type 2 (ATD2). An autosomal recessive chondrodysplasia characterized by a severely constricted thoracic cage, short-limbed short stature, and polydactyly. It often leads to death in infancy because of respiratory insufficiency. Retinal degeneration, cystic renal disease and hepatic disease can be present in affected individuals who survive early childhood.

Chromosomal Location of Human Ortholog: 3q25.33

Cellular Component: centrosome; cilium; cytoplasm

Biological Process: cilium biogenesis; organelle organization and biogenesis

Disease: Short-rib Thoracic Dysplasia 2 With Or Without Polydactyly
Research Articles on IFT80
1. Mutations in IFT80 can be responsible for a lethal form of short-rib polydactyly and provide the molecular basis for the Jeune-Verma-Naumoff dysplasia spectrum.
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Precautions
All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
Disclaimer
While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
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