Product Name
Consortin (Cnst), Recombinant Protein
Full Product Name
Recombinant Mouse Consortin (Cnst)
Product Gene Name
Cnst recombinant protein
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Research Use Only
For Research Use Only. Not for use in diagnostic procedures.
Sequence Positions
1-711aa; full length protein
Sequence
MDDSDPPTYS LQIEPQDGCH PGDSVERRVT RLPSVSDENE NQLAGDGPAG LTTSEGAMGR ATVSEQDSLN NNESFPSSCE AAPTENAENT PSEGPKDDPP SLGQDQKLPA KRSPRAKKSS PKSAPPGDAV PVMQTQNATS QAAGEEEAAG VNANDPPKAP ALQPLFSLIR GEVAQMDSRA LPLFLHQVAE TYFQEEDYEK AMKFIQLERL YHEQLLANLS AIQEQWETKW KAVQPRTVTP LRNSEKGFNG EDFEQLAKIC TTHQDPLLSK LKTAPVEPSP ERKSLARAIM SEEAVGTEAA AKEPEIETCP STDPSGDRHE EEPQESSPGC HQMEWQTASP ELPGTAGKDH TEELPSSTNA TLDLHTQSLE TAGSRSGPAA ASNACKDSSC VPAPPTEDHC GVARDPKVAP PSESVAEQKL STGDDGALPG LISEGKYSQA HRKELCLPLQ DAFEALPRDQ PHSSEVAEPR QPDVTASDGK SAQSQAGLET GPESALCGDR KACDVSTLCL EVCMAPEERR DSEDRVSKET EDYLHSLLER CLKDAEDSLS YEDIQDDDSD LLQDLSPEEA SYSLQEDLPP DESTLSLDDL AKKIEIAEAI PAEGLVSILK KRNDTVGSHP AQMQQKPAKR RVRFQEIDDN LEQDEVGGGS CILLILLCIA TVFLSVGGTA LYCTLGNIES PVCTDFADNV DFYYTKLLQG VAGLKHWVYL S
3D Structure
ModBase 3D Structure for Q8CBC4
Host
Cell Free Expression
Form/Format
Liquid containing glycerol
Storage Buffer
Tris-based buffer, 50% glycerol.
Preparation and Storage
Store at -20 degree C, for extended storage, conserve at -20 degree C or -80 degree C.
Repeated freezing and thawing is not recommended. Store working aliquots at 4 degree C for up to one week.
ISO Certification
Manufactured in an ISO 13485:2003 and EN ISO 13485:2012 Certified Laboratory.
Other Notes
Small volumes of Cnst recombinant protein vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
Product Categories/Family for Cnst recombinant protein
Transmembrane Protein
Application Notes for Cnst recombinant protein
This is a recombinant transmembrane protein expressed in a cell-free expression system.
NCBI/Uniprot data below describe general gene information for Cnst. It may not necessarily be applicable to this product.
NCBI Accession #
NP_666217.2
[Other Products]
NCBI GenBank Nucleotide #
NM_146105.3
[Other Products]
UniProt Primary Accession #
Q8CBC4
[Other Products]
UniProt Secondary Accession #
Q8BFS5; Q8K053[Other Products]
UniProt Related Accession #
Q8CBC4[Other Products]
Molecular Weight
45,414 Da
NCBI Official Full Name
consortin
NCBI Official Synonym Full Names
consortin, connexin sorting protein
NCBI Official Symbol
Cnst??[Similar Products]
NCBI Official Synonym Symbols
9630058J23Rik
??[Similar Products]
NCBI Protein Information
consortin
UniProt Protein Name
Consortin
UniProt Gene Name
Cnst??[Similar Products]
UniProt Entry Name
CNST_MOUSE
UniProt Comments for Cnst
CNST: Required for targeting of connexins to the plasma membrane. Belongs to the CNST family. 3 isoforms of the human protein are produced by alternative splicing.
Protein type: Membrane protein, integral
Cellular Component: cytoplasmic vesicle; Golgi apparatus; integral to membrane; membrane; plasma membrane; protein complex; trans-Golgi network; transport vesicle
Molecular Function: phosphatase binding; protein binding
Biological Process: positive regulation of Golgi to plasma membrane protein transport
Research Articles on Cnst
1. Consortin is a trans-Golgi network cargo receptor for the plasma membrane targeting and recycling of connexins.
Precautions
All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
Disclaimer
While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.
It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
