Product Name
Methylmalonic aciduria and homocystinuria type D homolog, mitochondrial (Mmadhc), Recombinant Protein
Full Product Name
Recombinant Mouse Methylmalonic aciduria and homocystinuria type D homolog, mitochondrial (Mmadhc)
Product Gene Name
Mmadhc recombinant protein
[Similar Products]
Product Synonym Gene Name
Mmadhc[Similar Products]
Research Use Only
For Research Use Only. Not for use in diagnostic procedures.
Sequence Positions
39-296aa, Full Length of Mature Protein
Sequence
SDESHVATAP PDICSRTVWP DETMGPFGPQ DQRFQLPGNI GFDCHLNGTA SQKKSQAHKT LPDVLAEPLS TERHEFVMAQ YVNEFQDSDA PVEQEINSAE TYFESAKVEC AIQTCPELLR RDFESLFPEV ANSKLMILTV TQKTENDMTV WSEEVEVERE VLLEKFISGA KEICYALRAE GYWADFIDPS SGVAFFGPYT NNTLFETDER YRHLGFSVDD LGCCKVIRHS LWGTHVVVGS IFTNATADSS IMRKLSGN
3D Structure
ModBase 3D Structure for Q99LS1
Host
E Coli or Yeast or Baculovirus or Mammalian Cell
Purity/Purification
>85% (SDS-PAGE) (lot specific)
Form/Format
Liquid containing glycerol
Tag Information
This protein contains an N-terminal tag and may also contain a C-terminal tag. Tag types are determined by various factors including tag-protein stability, please inquire for tag information.
Sterility
Sterile filter available upon request.
Endotoxin
Low endotoxin available upon request.
Storage Buffer
Tris-based buffer, 50% glycerol
Preparation and Storage
Store at -20 degrees C. For long-term storage, store at -20 degrees C or -80 degrees C. Store working aliquots at 4 degrees C for up to one week. Repeated freezing and thawing is not recommended.
ISO Certification
Manufactured in an ISO 13485:2003 and EN ISO 13485:2012 Certified Laboratory.
Other Notes
Small volumes of Mmadhc recombinant protein vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
NCBI/Uniprot data below describe general gene information for Mmadhc. It may not necessarily be applicable to this product.
NCBI Accession #
NP_598600.1
[Other Products]
NCBI GenBank Nucleotide #
NM_133839.3
[Other Products]
UniProt Primary Accession #
Q99LS1
[Other Products]
UniProt Related Accession #
Q99LS1[Other Products]
Molecular Weight
32,995 Da
NCBI Official Full Name
methylmalonic aciduria and homocystinuria type D homolog, mitochondrial isoform 1
NCBI Official Synonym Full Names
methylmalonic aciduria (cobalamin deficiency) cblD type, with homocystinuria
NCBI Official Symbol
Mmadhc??[Similar Products]
NCBI Official Synonym Symbols
CblD; AI314967; 2010311D03Rik
??[Similar Products]
NCBI Protein Information
methylmalonic aciduria and homocystinuria type D homolog, mitochondrial
UniProt Protein Name
Methylmalonic aciduria and homocystinuria type D homolog, mitochondrial
UniProt Synonym Protein Names
CblD
Protein Family
Methylmalonic aciduria and homocystinuria
UniProt Gene Name
Mmadhc??[Similar Products]
UniProt Comments for Mmadhc
Involved in cobalamin metabolism. Plays a role in regulating the biosynthesis of two coenzymes, methylcobalamin and adenosylcobalamin. Plays a role in regulating the proportion of methylcobalamin and adenosylcobalamin. Promotes oxidation of cob(II)alamin bound to MMACHC.
Research Articles on Mmadhc
1. During organogenesis Mmachc and Mmadhc may interact in only a subset of cells.
Precautions
All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
Disclaimer
While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.
It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
