Product Name
Lactoferrin (LTF), Native Protein
Full Product Name
Lactoferrin
Product Gene Name
LTF native protein
[Similar Products]
Research Use Only
For Research Use Only. Not for use in diagnostic procedures.
Purity/Purification
Purified
ISO Certification
Manufactured in an ISO 13485:2003 and EN ISO 13485:2012 Certified Laboratory.
Other Notes
Small volumes of LTF native protein vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
Product Categories/Family for LTF native protein
Purified Gastro
Applications Tested/Suitable for LTF native protein
Lateral Flow (LF), Control (CON)
NCBI/Uniprot data below describe general gene information for LTF. It may not necessarily be applicable to this product.
NCBI Accession #
AAB57795.1
[Other Products]
UniProt Secondary Accession #
O00756; Q16780; Q16785; Q16786; Q16789; Q5DSM0; Q8IU92; A8K9U8; B2MV13; B7Z4X2; E7EQH5[Other Products]
UniProt Related Accession #
P02788[Other Products]
Molecular Weight
73,161 Da[Similar Products]
NCBI Official Full Name
lactoferrin, partial
NCBI Official Synonym Full Names
lactotransferrin
NCBI Official Symbol
LTF??[Similar Products]
NCBI Official Synonym Symbols
LF; HLF2; GIG12; HEL110
??[Similar Products]
NCBI Protein Information
lactotransferrin
UniProt Protein Name
Lactotransferrin
UniProt Synonym Protein Names
Growth-inhibiting protein 12; Talalactoferrin
Protein Family
Lactotransferrin
UniProt Gene Name
LTF??[Similar Products]
UniProt Synonym Gene Names
GIG12; LF; Lactoferrin; Lfcin-H??[Similar Products]
NCBI Summary for LTF
This gene is a member of the transferrin family of genes and its protein product is found in the secondary granules of neutrophils. The protein is a major iron-binding protein in milk and body secretions with an antimicrobial activity, making it an important component of the non-specific immune system. The protein demonstrates a broad spectrum of properties, including regulation of iron homeostasis, host defense against a broad range of microbial infections, anti-inflammatory activity, regulation of cellular growth and differentiation and protection against cancer development and metastasis. Antimicrobial, antiviral, antifungal and antiparasitic activity has been found for this protein and its peptides. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Sep 2014]
UniProt Comments for LTF
Transferrins are iron binding transport proteins which can bind two Fe3+ ions in association with the binding of an anion, usually bicarbonate.
Research Articles on LTF
1. It has been shown that LF expression in breast tumors correlated with life expectancy of Breast Cancer patients and important physiologic and clinical features of the disease, while the character of such relation strongly depended on molecular phenotype of tumor, i.e. luminal A, luminal B or basal.
Precautions
All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
Disclaimer
While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.
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