Full Product Name
GH1 Antibody
Product Synonym Names
gH; GH-N; GH1; GHB5; GHN; Growth hormone 1; Growth hormone; Growth hormone B5; Growth hormone, normal; Growth hormone, pituitary; HG1; hGH-N; IGHD1B; Pituitary growth hormone; RNGHGP; SOMA_HUMAN; Somatotropin
Product Gene Name
anti-GH1 antibody
[Similar Products]
Research Use Only
For Research Use Only. Not for use in diagnostic procedures.
3D Structure
ModBase 3D Structure for P01241
Specificity
GH1 antibody detects endogenous levels of total GH1
Purity/Purification
The antiserum was purified by peptide affinity chromatography using SulfoLink Coupling Resin.
Form/Format
Liquid
Phosphate buffered saline, pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Concentration
1mg/ml (lot specific)
Immunogen
A synthesized peptide derived from human GH1
Subcellular Location
Secreted.
Preparation and Storage
Store at -20 degree C. Stable for 12 months from date of receipt.
ISO Certification
Manufactured in an ISO 9001:2015 Certified Laboratory.
Supply Chain Verification
Manufactured in a lab with traceable raw materials manufactured on site. Coordinated product portfolio of antibodies, pairs, conjugates, recombinant proteins, and immunoassay materials available, please inquire.
Other Notes
Small volumes of anti-GH1 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
Related Product Information for
anti-GH1 antibody
Function: Plays an important role in growth control. Its major role in stimulating body growth is to stimulate the liver and other tissues to secrete IGF-1. It stimulates both the differentiation and proliferation of myoblasts. It also stimulates amino acid uptake and protein synthesis in muscle and other tissues.
Subunit Structure: Monomer, dimer, trimer, tetramer and pentamer, disulfide-linked or non-covalently associated, in homopolymeric and heteropolymeric combinations. Can also form a complex either with GHBP or with the alpha2-macroglobulin complex.
Similarity: Belongs to the somatotropin/prolactin family.
Applications Tested/Suitable for anti-GH1 antibody
Western Blot (WB), ELISA (EIA)
Application Notes for anti-GH1 antibody
WB: 1:1000-3000
Western Blot (WB) of anti-GH1 antibody
Western blot analysis GH1 using COLO205 whole cell lysates
NCBI/Uniprot data below describe general gene information for GH1. It may not necessarily be applicable to this product.
NCBI Accession #
NP_000506.2
[Other Products]
NCBI GenBank Nucleotide #
NM_000515.4
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UniProt Primary Accession #
P01241
[Other Products]
UniProt Secondary Accession #
Q14405; Q16631; Q5EB53; Q9HBZ1; Q9UMJ7; Q9UNL5; A6NEF6[Other Products]
UniProt Related Accession #
P01241[Other Products]
Molecular Weight
Observed: 25 kDa
Predicted: 25 kDa
NCBI Official Full Name
somatotropin isoform 1
NCBI Official Synonym Full Names
growth hormone 1
NCBI Official Symbol
GH1??[Similar Products]
NCBI Official Synonym Symbols
GH; GHN; GH-N; GHB5; hGH-N; IGHD1B
??[Similar Products]
NCBI Protein Information
somatotropin
UniProt Protein Name
Somatotropin
UniProt Synonym Protein Names
Growth hormone; GH; GH-N; Growth hormone 1; Pituitary growth hormone
Protein Family
Somatotropin
UniProt Gene Name
GH1??[Similar Products]
UniProt Synonym Gene Names
GH; GH-N??[Similar Products]
NCBI Summary for GH1
The protein encoded by this gene is a member of the somatotropin/prolactin family of hormones which play an important role in growth control. The gene, along with four other related genes, is located at the growth hormone locus on chromosome 17 where they are interspersed in the same transcriptional orientation; an arrangement which is thought to have evolved by a series of gene duplications. The five genes share a remarkably high degree of sequence identity. Alternative splicing generates additional isoforms of each of the five growth hormones, leading to further diversity and potential for specialization. This particular family member is expressed in the pituitary but not in placental tissue as is the case for the other four genes in the growth hormone locus. Mutations in or deletions of the gene lead to growth hormone deficiency and short stature. [provided by RefSeq, Jul 2008]
UniProt Comments for GH1
Plays an important role in growth control. Its major role in stimulating body growth is to stimulate the liver and other tissues to secrete IGF-1. It stimulates both the differentiation and proliferation of myoblasts. It also stimulates amino acid uptake and protein synthesis in muscle and other tissues.
Research Articles on GH1
1. Patients examined at 1 year or several years from complicated mild traumatic brain injury had a similarly high occurrence of isolated GH deficiency
Precautions
All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
Disclaimer
While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.
It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
