Product Name
Epigen (EPGN), Polyclonal Antibody
Popular Item
Full Product Name
Anti-Epigen Antibody
Product Synonym Names
Epigen; Epithelial mitogen; EPG
Product Gene Name
anti-EPGN antibody
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Antibody/Peptide Pairs
Epigen peptide (MBS8243350) is used for blocking the activity of Epigen antibody (MBS8241983)
Research Use Only
For Research Use Only. Not for use in diagnostic procedures.
3D Structure
ModBase 3D Structure for Q6UW88
Specificity
Recognizes endogenous levels of Epigen protein.
Purity/Purification
The antibody was purified by immunogen affinity chromatography.
Form/Format
Liquid in 0.42% Potassium Phosphate, 0.87% Sodium Chloride, pH 7.3, 30% Glycerol, and 0.01% Sodium Azide.
Immunogen
KLH-conjugated synthetic peptide encompassing a sequence within the center region of human Epigen. The exact sequence is proprietary.
Preparation and Storage
Shipping : Blue Ice
Upon delivery aliquot and store at -20°C for one year. Avoid freeze/thaw cycles.
Other Notes
Small volumes of anti-EPGN antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
Related Product Information for
anti-EPGN antibody
Rabbit polyclonal antibody to Epigen
Applications Tested/Suitable for anti-EPGN antibody
Western Blot (WB)
Application Notes for anti-EPGN antibody
Western Blot: (1/500 - 1/1000)
Western Blot (WB) of anti-EPGN antibody
Western blot analysis of Epigen expression in HEK293T (A) whole cell lysates.
NCBI/Uniprot data below describe general gene information for EPGN. It may not necessarily be applicable to this product.
NCBI Accession #
Q6UW88.2
[Other Products]
UniProt Primary Accession #
Q6UW88
[Other Products]
UniProt Secondary Accession #
A1BMM3; A1BMM4; A1BMM5; A1BMM6; A1BMM7; A1BMM8; A8K090[Other Products]
UniProt Related Accession #
Q6UW88[Other Products]
NCBI Official Full Name
Epigen
NCBI Official Synonym Full Names
epithelial mitogen
NCBI Official Symbol
EPGN??[Similar Products]
NCBI Official Synonym Symbols
EPG; PRO9904; ALGV3072
??[Similar Products]
NCBI Protein Information
epigen
UniProt Protein Name
Epigen
UniProt Synonym Protein Names
Epithelial mitogen; EPG
UniProt Gene Name
EPGN??[Similar Products]
UniProt Synonym Gene Names
EPG??[Similar Products]
UniProt Entry Name
EPGN_HUMAN
NCBI Summary for EPGN
The protein encoded by this gene is a member of the epidermal growth factor family. Members of this family are ligands for the epidermal growth factor receptor and play a role in cell survival, proliferation and migration. This protein has been reported to have high mitogenic activity but low affinity for its receptor. Expression of this transcript and protein have been reported in cancer specimens of the breast, bladder, and prostate. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Aug 2012]
UniProt Comments for EPGN
Epigen: Promotes the growth of epithelial cells. May stimulate the phosphorylation of EGFR and mitogen-activated protein kinases. 7 isoforms of the human protein are produced by alternative splicing.
Protein type: Membrane protein, integral; Ligand, receptor tyrosine kinase
Chromosomal Location of Human Ortholog: 4q13.3
Cellular Component: extracellular space; integral to plasma membrane; intracellular
Molecular Function: epidermal growth factor receptor binding; growth factor activity
Biological Process: activation of MAPK activity; angiogenesis; epidermal growth factor receptor signaling pathway; MAPKKK cascade; positive regulation of cell proliferation; positive regulation of epidermal growth factor receptor activity; positive regulation of epithelial cell proliferation; positive regulation of MAP kinase activity; positive regulation of mitosis
Research Articles on EPGN
1. cloning of a related gene in mouse
Precautions
All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
Disclaimer
While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.
It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
