Product Name
Growth Hormone (GH1), Polyclonal Antibody
Full Product Name
Anti-rat Growth Hormone antibody
Product Synonym Names
Somatotropin; growth hormone 1; gH antibody; GH-N antibody; GH1 antibody; Growth hormone 1 antibody; Growth hormone antibody; hGH-N antibody; IGHD1B antibody; Pituitary growth hormone antibody; Somatotropin antibody
Product Gene Name
anti-GH1 antibody
[Similar Products]
Research Use Only
For Research Use Only. Not for use in diagnostic procedures.
3D Structure
ModBase 3D Structure for P01244
Purity/Purification
Immunogen affinity purified.
Immunogen
E Coli-derived rat GH recombinant protein (Position: F27-F216).
Contents
Each vial contains 0.9mg NaCl, 0.2mg Na2HPO4, 0.05mg NaN3.
Reconstitution
Add 0.2ml of distilled water will yield a concentration of 500ug/ml.
Preparation and Storage
At -20 degree C for one year. After reconstitution, at 4 degree C for one month. It can also be aliquotted and stored frozen at -20 degree C for a longer time. Avoid repeated freezing and thawing.
ISO Certification
Manufactured in an ISO 13485:2003 and EN ISO 13485:2012 Certified Laboratory.
Other Notes
Small volumes of anti-GH1 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
Related Product Information for
anti-GH1 antibody
Description: Rabbit IgG polyclonal antibody for Somatotropin(GH1) detection. Tested with WB, IHC-P, ELISA, Neu, IP in Rat.
Background: Growth Hormone(GH) is mapped to 17q22-q24. Human growth hormone has a molecular mass of 22,005 and contains 191 amino acid residues with 2 disulfide bridges. Rat GH shares 98% amino acid sequence homology with mouse. It binds two receptor molecules and thereby induces signal transduction through receptor dimerization. At high concentrations, GH acts as an antagonist because of a large difference in affinities at the respective s.
Applications Tested/Suitable for anti-GH1 antibody
Western Blot (WB), Immunohistochemistry (IHC) Paraffin, ELISA (EIA), Neu, Immunoprecipitation (IP)
Western Blot (WB) of anti-GH1 antibody
Anti-rat Growth Hormone antibody, MBS175387, Western blotting
Lane 1: Recombinant Rat GH Protein 10ng
Lane 2: Recombinant Rat GH Protein 5ng
Lane 3: Recombinant Rat GH Protein 2
NCBI/Uniprot data below describe general gene information for GH1. It may not necessarily be applicable to this product.
NCBI Accession #
P01244.1
[Other Products]
UniProt Primary Accession #
P01244
[Other Products]
UniProt Related Accession #
P01244[Other Products]
Molecular Weight
24,656 Da
NCBI Official Full Name
Somatotropin
NCBI Official Synonym Full Names
growth hormone 1
NCBI Official Symbol
Gh1??[Similar Products]
NCBI Official Synonym Symbols
Gh; RNGHGP
??[Similar Products]
NCBI Protein Information
somatotropin
UniProt Protein Name
Somatotropin
UniProt Synonym Protein Names
Growth hormone
Protein Family
Growth hormone
UniProt Gene Name
Gh1??[Similar Products]
UniProt Synonym Gene Names
Gh??[Similar Products]
UniProt Entry Name
SOMA_RAT
NCBI Summary for GH1
ligand for growth hormone receptor; plays a role in a number of signaling pathways [RGD, Feb 2006]
UniProt Comments for GH1
Plays an important role in growth control. Its major role in stimulating body growth is to stimulate the liver and other tissues to secrete IGF-1. It stimulates both the differentiation and proliferation of myoblasts. It also stimulates amino acid uptake and protein synthesis in muscle and other tissues.
Research Articles on GH1
1. Linear growth impairment in chronic kidney disease can in part be explained by impaired long bone growth plate growth hormone receptor signaling through the JAK2/STAT5 pathway.
Precautions
All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
Disclaimer
While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.
It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
