Product Name
SLC30A8, Polyclonal Antibody
Full Product Name
SLC30A8 antibody - middle region
Product Gene Name
anti-SLC30A8 antibody
[Similar Products]
Product Synonym Gene Name
ZnT-8; ZNT8[Similar Products]
Antibody/Peptide Pairs
SLC30A8 peptide (MBS3233816) is used for blocking the activity of SLC30A8 antibody (MBS3208851)
Research Use Only
For Research Use Only. Not for use in diagnostic procedures.
Immunogen Sequence
Synthetic peptide located within the following region: LLIDLTSFLL SLFSLWLSSK PPSKRLTFGW HRAEILGALL SILCIWVVTG
3D Structure
ModBase 3D Structure for Q8IWU4
Species Reactivity
Cow, Dog, Horse, Human, Mouse, Pig, Rabbit, Rat, Zebrafish
Purity/Purification
Affinity Purified
Form/Format
Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.
Homology
Cow: 82%; Dog: 93%; Horse: 100%; Human: 100%; Mouse: 93%; Pig: 100%; Rabbit: 93%; Rat: 93%; Zebrafish: 75%
Immunogen
The immunogen is a synthetic peptide directed towards the middle region of human SLC30A8
Preparation and Storage
For short term use, store at 2-8 degree C up to 1 week. For long term storage, store at -20 degree C in small aliquots to prevent freeze-thaw cycles.
Other Notes
Small volumes of anti-SLC30A8 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
Related Product Information for
anti-SLC30A8 antibody
This is a rabbit polyclonal antibody against SLC30A8. It was validated on Western Blot using a cell lysate as a positive control.
Target Description: The protein encoded by this gene is a zinc efflux transporter involved in the accumulation of zinc in intracellular vesicles. This gene is expressed at a high level only in the pancreas, particularly in islets of Langerhans. The encoded protein colocalize
Product Categories/Family for anti-SLC30A8 antibody
Polyclonal; Membrane Protein;
Applications Tested/Suitable for anti-SLC30A8 antibody
Western Blot (WB)
Western Blot (WB) of anti-SLC30A8 antibody
WB Suggested Anti-SLC30A8 Antibody Titration: 0.2-1 ug/ml
Positive Control: NCI-H226 cell lysate
NCBI/Uniprot data below describe general gene information for SLC30A8. It may not necessarily be applicable to this product.
NCBI Accession #
NP_776250
[Other Products]
NCBI GenBank Nucleotide #
NM_173851
[Other Products]
UniProt Primary Accession #
Q8IWU4
[Other Products]
UniProt Related Accession #
Q8IWU4[Other Products]
NCBI Official Full Name
zinc transporter 8 isoform a
NCBI Official Synonym Full Names
solute carrier family 30 member 8
NCBI Official Symbol
SLC30A8??[Similar Products]
NCBI Official Synonym Symbols
ZNT8; ZnT-8
??[Similar Products]
NCBI Protein Information
zinc transporter 8
UniProt Protein Name
Zinc transporter 8
UniProt Synonym Protein Names
Solute carrier family 30 member 8
Protein Family
Zinc transporter
UniProt Gene Name
SLC30A8??[Similar Products]
UniProt Synonym Gene Names
ZNT8; ZnT-8??[Similar Products]
UniProt Entry Name
ZNT8_HUMAN
NCBI Summary for SLC30A8
The protein encoded by this gene is a zinc efflux transporter involved in the accumulation of zinc in intracellular vesicles. This gene is expressed at a high level only in the pancreas, particularly in islets of Langerhans. The encoded protein colocalizes with insulin in the secretory pathway granules of the insulin-secreting INS-1 cells. Allelic variants of this gene exist that confer susceptibility to diabetes mellitus, noninsulin-dependent (NIDDM). Several transcript variants encoding different isoforms have been found for this gene.[provided by RefSeq, Mar 2010]
Research Articles on SLC30A8
1. Polymorphisms in SLC30A8 is associated with Polycystic ovary syndrome and type-2 diabetes.
Precautions
All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
Disclaimer
While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.
It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
