Rat Monoclonal [clone M7I-3] (IgG) to Human ABCC10; ABCC10; EST182763; Multidrug resistance protein 7; MRP7; SIMRP7

For Research Use Only. Not for use in diagnostic procedures.

Polyclonal

IgG

Rabbit

MRP7 Antibody detects endogenous levels of total MRP7 protein.

Immunoaffinity Purified

PBS (without Mg2+, Ca2+), pH 7.4, 150 mM sodium chloride, 0.02% sodium azide, 50% glycerol

Store at -20 degree C for up to one year.

Small volumes of anti-ABCC10 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

ABCC10 is a member of the superfamily of ATP-binding cassette (ABC)transporters. ABC proteins transport various molecules across extra- and intra-cellular membranes. ABC genes are divided into seven distinct subfamilies (ABC1, MDR/TAP, MRP, ALD, OABP, GCN20, and White). This ABC full-transporter is a member of the MRP subfamily which is involved in multi-drug resistance. Multiple transcript variants encoding different isoforms have been found for this gene.

Transporter; ATP-binding cassette - ABCC/MRP

ELISA (EIA), Immunohistochemistry (IHC) Paraffin, Western Blot (WB)

ELISA: 1:40000
IHC-P: 1:50
WB: 1:500-1:1000

Human Kidney: Formalin-Fixed, Paraffin-Embedded (FFPE)

Western blot of extracts from COLO/COS7 cells, using MRP7 Antibody. The lane on the right is treated with the synthesized peptide.

158,781 Da

ATP binding cassette subfamily C member 10

multidrug resistance-associated protein 7

Multidrug resistance-associated protein 7

MRP7; SIMRP7??[Similar Products]

The protein encoded by this gene is a member of the superfamily of ATP-binding cassette (ABC) transporters. ABC proteins transport various molecules across extra- and intra-cellular membranes. ABC genes are divided into seven distinct subfamilies (ABC1, MDR/TAP, MRP, ALD, OABP, GCN20, and White). This ABC full-transporter is a member of the MRP subfamily which is involved in multi-drug resistance. Multiple transcript variants encoding different isoforms have been found for this gene.[provided by RefSeq, Nov 2010]

ATP-dependent transporter probably involved in cellular detoxification through lipophilic anion extrusion.

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