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ABO, cDNA Clone

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產(chǎn)品名稱: ABO, cDNA Clone
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ABO, cDNA Clone


ABO, cDNA Clone  的詳細(xì)介紹
Product Name

ABO, cDNA Clone

Full Product Name

ABO cDNA Clone

Product Gene Name

ABO cdna clone

[Similar Products]
Research Use Only
For Research Use Only. Not for use in diagnostic procedures.
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Sequence
ATGGCCGAGG TGTTGCGGAC GCTGGCCGGA AAACCAAAAT GCCACGCACT TCGACCTATG ATCCTTTTCC TAATAATGCT TGTCTTGGTC TTGTTTGGTT ACGGGGTCCT AAGCCCCAGA AGTCTAATGC CAGGAAGCCT GGAACGGGGG TTCTGCATGG CTGTTAGGGA ACCTGACCAT CTGCAGCGCG TCTCGTTGCC AAGGATGGTC TACCCCCAGC CAAAGGTGCT GACACCGTGT AGGAAGGATG TCCTCGTGGT GACCCCTTGG CTGGCTCCCA TTGTCTGGGA GGGCACATTC AACATCGACA TCCTCAACGA GCAGTTCAGG CTCCAGAACA CCACCATTGG GTTAACTGTG TTTGCCATCA AGAAATACGT GGCTTTCCTG AAGCTGTTCC TGGAGACGGC GGAGAAGCAC TTCATGGTGG GCCACCGTGT CCACTACTAT GTCTTCACCG ACCAGCCGGC CGCGGTGCCC CGCGTGACGC TGGGGACCGG TCGGCAGCTG TCAGTGCTGG AGGTGCGCGC CTACAAGCGC TGGCAGGACG TGTCCATGCG CCGCATGGAG ATGATCAGTG ACTTCTGCGA GCGGCGCTTC CTCAGCGAGG TGGATTACCT GGTGTGCGTG GACGTGGACA TGGAGTTCCG CGACCACGTG GGCGTGGAGA TCCTGACTCC GCTGTTCGGC ACCCTGCACC CCGGCTTCTA CGGAAGCAGC CGGGAGGCCT TCACCTACGA GCGCCGGCCC CAGTCCCAGG CCTACATCCC CAAGGACGAG GGCGATTTCT ACTACCTGGG GGGGTTCTTC GGGGGGTCGG TGCAAGAGGT GCAGCGGCTC ACCAGGGCCT GCCACCAGGC CATGATGGTC GACCAGGCCA ACGGCATCGA GGCCGTGTGG CACGACGAGA GCCACCTGAA CAAGTACCTG CTGCGCCACA AACCCACCAA GGTGCTCTCC CCCGAGTACT TGTGGGACCA GCAGCTGCTG GGCTGGCCCG CCGTCCTGAG GAAGCTGAGG TTCACTGCGG TGCCCAAGAA CCACCAGGCG GTCCGGAACC CGTGA
OMIM
110300
Vector
pENTR223.1 or pUC
Clone Sequence Report
Provided with product shipment
ISO Certification
Manufactured in an ISO 13485:2003 and EN ISO 13485:2012 Certified Laboratory.
Other Notes
Small volumes of ABO cdna clone vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
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NCBI/Uniprot data below describe general gene information for ABO. It may not necessarily be applicable to this product.
NCBI GI #
109730364
NCBI GeneID
28
NCBI Accession #
BC111575 [Other Products]
UniProt Secondary Accession #
O14758; Q14490; Q53I57; Q6ISD4; Q6KFZ2; Q70V27; Q99484; Q99485; Q9NY01; Q9UQ68; B0JDB9[Other Products]
UniProt Related Accession #
P16442[Other Products]
Molecular Weight
40,934 Da
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NCBI Official Full Name
Homo sapiens ABO blood group (transferase A, alpha 1-3-N-acetylgalactosaminyltransferase; transferase B, alpha 1-3-galactosyltransferase), mRNA
NCBI Official Synonym Full Names
ABO blood group (transferase A, alpha 1-3-N-acetylgalactosaminyltransferase; transferase B, alpha 1-3-galactosyltransferase)
NCBI Official Symbol
ABO??[Similar Products]
NCBI Official Synonym Symbols
GTB; NAGAT; A3GALNT; A3GALT1
??[Similar Products]
NCBI Protein Information
histo-blood group ABO system transferase
UniProt Protein Name
Histo-blood group ABO system transferase
UniProt Synonym Protein Names
Fucosylglycoprotein 3-alpha-galactosyltransferase; Fucosylglycoprotein alpha-N-acetylgalactosaminyltransferase; Glycoprotein-fucosylgalactoside alpha-N-acetylgalactosaminyltransferase (EC:2.4.1.40
Protein Family
Abortive infection protein
UniProt Gene Name
ABO??[Similar Products]
UniProt Synonym Gene Names
A transferase; B transferase??[Similar Products]
UniProt Entry Name
BGAT_HUMAN
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NCBI Summary for ABO
This gene encodes proteins related to the first discovered blood group system, ABO. Which allele is present in an individual determines the blood group. The 'O' blood group is caused by a deletion of guanine-258 near the N-terminus of the protein which results in a frameshift and translation of an almost entirely different protein. Individuals with the A, B, and AB alleles express glycosyltransferase activities that convert the H antigen into the A or B antigen. Other minor alleles have been found for this gene. [provided by RefSeq, Jul 2008]
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UniProt Comments for ABO
ABO: This protein is the basis of the ABO blood group system. The histo-blood group ABO involves three carbohydrate antigens: A, B, and H. A, B, and AB individuals express a glycosyltransferase activity that converts the H antigen to the A antigen (by addition of UDP-GalNAc) or to the B antigen (by addition of UDP-Gal), whereas O individuals lack such activity. Belongs to the glycosyltransferase 6 family.

Protein type: Membrane protein, integral; EC 2.4.1.37; Glycan Metabolism - glycosphingolipid biosynthesis - lacto and neolacto series; Transferase; EC 2.4.1.40

Chromosomal Location of Human Ortholog: 9q34.2

Disease: Blood Group, Abo System
Research Articles on ABO
1. Data suggest women with blood groups A, B, O (i.e. non-AB) exhibit increased risk for gestational diabetes mellitus (GDM) compared with those with blood group AB; thus, glycosylation of the H antigen via NAGAT may be risk/protective factor for GDM.
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Precautions
All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
Disclaimer
While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
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