Full Product Name
DSP Antibody; FITC conjugated
Product Synonym Names
Desmoplakin; DP; 250/210 kDa paraneoplastic pemphigus antigen; DSP
Product Gene Name
anti-DSP antibody
[Similar Products]
Research Use Only
For Research Use Only. Not for use in diagnostic procedures.
3D Structure
ModBase 3D Structure for P15924
Purity/Purification
>95%,Protein G purified
Immunogen
Recombinant human Desmoplakin protein
Storage Buffer
Preservative: 0.03% Proclin 300 Constituents: 50% Glycerol, 0.01M PBS, PH 7.4
Santa Cruz Alternative
Potential replacement for Santa Cruz Biotechnology antibody catalog# sc-18083 / sc-18086 / sc-18082 / sc-33555
Preparation and Storage
Shipped at 4 degree C. Upon delivery, aliquot and store at -20 degree C or -80 degree C.
ISO Certification
Manufactured in an ISO 13485:2003 and EN ISO 13485:2012 Certified Laboratory.
Other Notes
Small volumes of anti-DSP antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
Related Product Information for
anti-DSP antibody
Major high molecular weight protein of desmosomes. Involved in the organization of the desmosomal cadherin-plakoglobin complexes into discrete plasma membrane domains and in the anchoring of intermediate filaments to the desmosomes.
Applications Tested/Suitable for anti-DSP antibody
ELISA (EIA)
NCBI/Uniprot data below describe general gene information for DSP. It may not necessarily be applicable to this product.
NCBI Accession #
NP_001008844.1
[Other Products]
NCBI GenBank Nucleotide #
NM_001008844.2
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UniProt Primary Accession #
P15924
[Other Products]
UniProt Secondary Accession #
O75993; Q14189; Q9UHN4; B2RTT2; D7RX09[Other Products]
UniProt Related Accession #
P15924[Other Products]
Molecular Weight
278,916 Da
NCBI Official Full Name
desmoplakin isoform II
NCBI Official Synonym Full Names
desmoplakin
NCBI Official Symbol
DSP??[Similar Products]
NCBI Official Synonym Symbols
DP; DCWHKTA
??[Similar Products]
NCBI Protein Information
desmoplakin
UniProt Protein Name
Desmoplakin
UniProt Synonym Protein Names
250/210 kDa paraneoplastic pemphigus antigen
Protein Family
Desmoplakin
UniProt Gene Name
DSP??[Similar Products]
UniProt Synonym Gene Names
DP??[Similar Products]
UniProt Entry Name
DESP_HUMAN
NCBI Summary for DSP
This gene encodes a protein that anchors intermediate filaments to desmosomal plaques and forms an obligate component of functional desmosomes. Mutations in this gene are the cause of several cardiomyopathies and keratodermas, including skin fragility-woolly hair syndrome. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jan 2016]
UniProt Comments for DSP
Major high molecular weight protein of desmosomes. Involved in the organization of the desmosomal cadherin-plakoglobin complexes into discrete plasma membrane domains and in the anchoring of intermediate filaments to the desmosomes.
Research Articles on DSP
1. There is higher incidence of Myocarditis in DSP mutation carriers affected by Arrhythmogenic right ventricular dysplasia.
Precautions
All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
Disclaimer
While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.
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