Product Name
nucleotide-binding oligomerization domain containing 2 (NOD2), ELISA Kit
Full Product Name
Bovine Nucleotide-binding oligomerization domain-containing protein 2, NOD2 ELISA Kit
Product Synonym Names
Bovine Nucleotide-binding oligomerization domain-containing protein 2 (NOD2) ELISA kit; ACUG; BLAU; CARD15; CD; CLR16.3; IBD1; NLRC2; NOD2B; PSORAS1; NLR family; CARD domain containing 2; NOD-like receptor C2; caspase recruitment domain family; member 15; caspase recruitment domain protei; nucleotide-binding oligomerization domain containing 2
Product Gene Name
NOD2 elisa kit
[Similar Products]
Research Use Only
For Research Use Only. Not for use in diagnostic procedures.
Request for Current Manual Insert
Request Current Manual
3D Structure
ModBase 3D Structure for Q6E804
Species Reactivity
Bovine
Preparation and Storage
Store all reagents at 2-8 degree C
Product Note
Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual.
Other Notes
Small volumes of NOD2 elisa kit vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
Searchable Terms for NOD2 purchase
MBS9333224 is a ready-to-use microwell, strip plate ELISA (enzyme-linked immunosorbent assay) Kit for analyzing the presence of the nucleotide-binding oligomerization domain containing 2 (NOD2) ELISA Kit target analytes in
biological samples. The concentration gradients of the kit standards or positive controls render a theoretical kit detection range in biological research samples containing NOD2. The ELISA analytical biochemical technique of the MBS9333224 kit is based on NOD2 antibody-NOD2 antigen interactions (immunosorbency) and an HRP colorimetric detection system to detect NOD2 antigen targets in samples. The ELISA Kit is designed to detect native, not recombinant, NOD2. Appropriate sample types may include undiluted body fluids and/or tissue homogenates, secretions. Quality control assays assessing reproducibility identified the intra-assay CV (%) and inter-assay CV(%).
NCBI/Uniprot data below describe general gene information for NOD2. It may not necessarily be applicable to this product.
NCBI Accession #
NP_001002889.1
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NCBI GenBank Nucleotide #
NM_001002889.1
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UniProt Primary Accession #
Q6E804
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UniProt Related Accession #
Q6E804[Other Products]
Molecular Weight
112,800 Da
NCBI Official Full Name
nucleotide-binding oligomerization domain-containing protein 2
NCBI Official Synonym Full Names
nucleotide-binding oligomerization domain containing 2<
NCBI Official Symbol
NOD2??[Similar Products]
NCBI Official Synonym Symbols
CARD15
??[Similar Products]
NCBI Protein Information
nucleotide-binding oligomerization domain-containing protein 2; caspase recruitment domain 15 protein; caspase recruitment domain-containing protein 15
UniProt Protein Name
Nucleotide-binding oligomerization domain-containing protein 2
UniProt Synonym Protein Names
Caspase recruitment domain-containing protein 15
Protein Family
Nucleotide-binding oligomerization domain-containing protein
UniProt Gene Name
NOD2??[Similar Products]
UniProt Synonym Gene Names
CARD15??[Similar Products]
UniProt Entry Name
NOD2_BOVIN
UniProt Comments for NOD2
Function: Recognizes muramyl dipeptide (MDP) constituents of bacterial peptidoglycans and plays a key role in gastrointestinal immunity: upon stimulation, binds the proximal adapter receptor-interacting RIPK2, which recruits ubiquitin ligases as XIAP, BIRC2, BIRC3 and the LUBAC complex, triggering activation of MAP kinases and activation of NF-kappa-B signaling, leading to activate the transcription of hundreds of genes involved in immune response
Research Articles on NOD2
1. A significant association was found between two polymorphisms of CARD15 and paratuberculosis status; cows with the heterozygous genotype were 3.35 times more likely to be infected than cows with the reference genotype.
Precautions
All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
Disclaimer
While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.
It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
