For Research Use Only. Not for use in diagnostic procedures.

Chromosome: 7; NC_000007.13 (75398842..75419064, complement). Location: 7q11.23

Affinity Purified
~90% by SDS-PAGE Purified by immunoaffinity chromatography.

Supplied as liquid in PBS pH7.4, 10% glycerol

May be stored at 4 degree C for short-term only. For long-term storage, aliquot and store at -20 degree C. Aliquots are stable for at least 6 months at -20 degree C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer.

Small volumes of CCL26 recombinant protein vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

CCL26 is a small cytokine belonging to the CC chemokine family that is also known as thymus and activation regulated chemokine (TARC). This protein is involved in immunoregulatory and inflammatory processes. It is expressed constitutively in thymus, but only transiently in phytohemagglutinin-stimulated peripheral blood mononuclear cells. It specifically binds and induces chemotaxis in T cells and elicits its effects by interacting with the chemokine receptor CCR4. CCL26, expressed in E. coli and purifed by conventional chromatography, after refolding of the isolated inclusion bodies in a renaturation buffer.

Growth Factors, Cytokines; Growth Factors-TARC

Suitable for use in ELISA and Western Blot.

8.5kD[Similar Products]

chemokine (C-C motif) ligand 26

C-C motif chemokine 26; eotaxin-3; MIP-4-alpha; chemokine N1; CC chemokine IMAC; OTTHUMP00000160954; OTTHUMP00000210227; thymic stroma chemokine-1; small inducible cytokine A26; small-inducible cytokine A26; macrophage inflammatory protein 4-alpha; small inducible cytokine subfamily A (Cys-Cys), member 26

C-C motif chemokine 26

SCYA26??[Similar Products]

CCL26_HUMAN

This gene is one of two Cys-Cys (CC) cytokine genes clustered on the q arm of chromosome 7. Cytokines are a family of secreted proteins involved in immunoregulatory and inflammatory processes. The CC cytokines are proteins characterized by two adjacent cysteines. The cytokine encoded by this gene displays chemotactic activity for normal peripheral blood eosinophils and basophils. The product of this gene is one of three related chemokines that specifically activate chemokine receptor CCR3. This chemokine may contribute to the eosinophil accumulation in atopic diseases. [provided by RefSeq]

Function: Chemotactic for eosinophils and basophils. Binds to CCR3.

Subunit structure: Monomer.

Subcellular location: Secreted.

Tissue specificity: Ubiquitously expressed at low levels in various tissues including heart and ovary.

Sequence similarities: Belongs to the intercrine beta (chemokine CC) family.

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