Human Tectonin beta-propeller repeat-containing protein 2 (TECPR2) ELISA kit; KIAA0297; KIAA0329; ; tectonin beta-propeller repeat containing 2

For Research Use Only. Not for use in diagnostic procedures.

Store all reagents at 2-8 degree C

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Small volumes of TECPR2 elisa kit vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

MBS9340832 is a ready-to-use microwell, strip plate ELISA (enzyme-linked immunosorbent assay) Kit for analyzing the presence of the tectonin beta-propeller repeat containing 2 (TECPR2) ELISA Kit target analytes in biological samples. The concentration gradients of the kit standards or positive controls render a theoretical kit detection range in biological research samples containing TECPR2. The ELISA analytical biochemical technique of the MBS9340832 kit is based on TECPR2 antibody-TECPR2 antigen interactions (immunosorbency) and an HRP colorimetric detection system to detect TECPR2 antigen targets in samples. The ELISA Kit is designed to detect native, not recombinant, TECPR2. Appropriate sample types may include undiluted body fluids and/or tissue homogenates, secretions. Quality control assays assessing reproducibility identified the intra-assay CV (%) and inter-assay CV(%).

153,848 Da

tectonin beta-propeller repeat containing 2

tectonin beta-propeller repeat-containing protein 2

Tectonin beta-propeller repeat-containing protein 2

KIAA0297; KIAA0329??[Similar Products]

TCPR2_HUMAN

The protein encoded by this gene is a member of the tectonin beta-propeller repeat-containing (TECPR) family, and contains both TECPR and tryptophan-aspartic acid repeat (WD repeat) domains. This gene has been implicated in autophagy, as reduced expression levels of this gene have been associated with impaired autophagy. Recessive mutations in this gene have been associated with a hereditary form of spastic paraparesis (HSP). HSP is characterized by progressive spasticity and paralysis of the legs. There is also some evidence linking mutations in this gene with birdshot chorioretinopathy (BSCR), which results in inflammation of the choroid and retina. Alternative splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq, Aug 2015]

TECPR2: Belongs to the WD repeat KIAA0329 family.

Protein type: Unknown function

Chromosomal Location of Human Ortholog: 14q32.31

Molecular Function: protein binding

Biological Process: autophagy

Disease: Spastic Paraplegia 49, Autosomal Recessive

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