Product Name
CCL27, Polyclonal Antibody
Popular Item
Full Product Name
CCL27 Antibody
Product Synonym Names
ALP; C-C motif chemokine 27; CC chemokine ILC; Ccl27; CCL27_HUMAN; Chemokine (C-C motif) ligand 27; CTACK; CTAK; Cutaneous T cell attracting chemokine; Cutaneous T-cell-attracting chemokine; ESkine; IL 11 R alpha locus chemokine; IL-11 R-alpha-locus chemokine; ILC; PESKY; SCYA27; Skinkine; Small inducible cytokine A27; small inducible cytokine subfamily A (Cys-Cys), member 27; Small-inducible cytokine A27
Product Gene Name
anti-CCL27 antibody
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Research Use Only
For Research Use Only. Not for use in diagnostic procedures.
3D Structure
ModBase 3D Structure for Q9Y4X3
Specificity
CCL27 antibody detects endogenous levels of total CCL27
Purity/Purification
The antiserum was purified by peptide affinity chromatography using SulfoLink Coupling Resin.
Form/Format
Liquid
Phosphate buffered saline, pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Concentration
1mg/ml (lot specific)
Immunogen
A synthesized peptide derived from human CCL27
Subcellular Location
Extracellular Region or Secreted
Tissue Specificity
Testis, thymus, placenta, ovary and skin.
Preparation and Storage
Store at -20 degree C. Stable for 12 months from date of receipt.
ISO Certification
Manufactured in an ISO 9001:2015 Certified Laboratory.
Supply Chain Verification
Manufactured in a lab with traceable raw materials manufactured on site. Coordinated product portfolio of antibodies, pairs, conjugates, recombinant proteins, and immunoassay materials available, please inquire.
Other Notes
Small volumes of anti-CCL27 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
Related Product Information for
anti-CCL27 antibody
Function: Chemotactic factor that attracts skin-associated memory T-lymphocytes. May play a role in mediating homing of lymphocytes to cutaneous sites. Binds to CCR10.
Subunit Structure: Monomer, dimer, and tetramer. Heparin avidly promotes oligomerization.
Similarity: Belongs to the intercrine beta (chemokine CC) family.
Applications Tested/Suitable for anti-CCL27 antibody
Western Blot (WB), ELISA (EIA)
Application Notes for anti-CCL27 antibody
WB: 1:1000-3000
Western Blot (WB) of anti-CCL27 antibody
Western blot analysis of CCL27 using Jurkat whole cell lysates

NCBI/Uniprot data below describe general gene information for CCL27. It may not necessarily be applicable to this product.
NCBI Accession #
NP_006655.1
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NCBI GenBank Nucleotide #
NM_006664.3
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UniProt Primary Accession #
Q9Y4X3
[Other Products]
UniProt Related Accession #
Q9Y4X3[Other Products]
Molecular Weight
Observed: 13 kDa
Predicted: 13 kDa
NCBI Official Full Name
C-C motif chemokine 27
NCBI Official Synonym Full Names
C-C motif chemokine ligand 27
NCBI Official Symbol
CCL27??[Similar Products]
NCBI Official Synonym Symbols
ALP; ILC; CTAK; CTACK; PESKY; ESKINE; SCYA27
??[Similar Products]
NCBI Protein Information
C-C motif chemokine 27
UniProt Protein Name
C-C motif chemokine 27
UniProt Synonym Protein Names
CC chemokine ILC; Cutaneous T-cell-attracting chemokine; CTACK; ESkine; IL-11 R-alpha-locus chemokine; Skinkine; Small-inducible cytokine A27
Protein Family
C-C motif chemokine
UniProt Gene Name
CCL27??[Similar Products]
UniProt Synonym Gene Names
ILC; SCYA27; CTACK??[Similar Products]
NCBI Summary for CCL27
This gene is one of several CC cytokine genes clustered on the p-arm of chromosome 9. Cytokines are a family of secreted proteins involved in immunoregulatory and inflammatory processes. The CC cytokines are proteins characterized by two adjacent cysteines. The protein encoded by this gene is chemotactic for skin-associated memory T lymphocytes. This cytokine may also play a role in mediating homing of lymphocytes to cutaneous sites. It specifically binds to chemokine receptor 10 (CCR10). Studies of a similar murine protein indicate that these protein-receptor interactions have a pivotal role in T cell-mediated skin inflammation. [provided by RefSeq, Sep 2014]
UniProt Comments for CCL27
Chemotactic factor that attracts skin-associated memory T-lymphocytes. May play a role in mediating homing of lymphocytes to cutaneous sites. Binds to CCR10.
Research Articles on CCL27
1. Plasma CCL27 levels were significantly lower in the VCA-IgA-negative normal subjects than in either the VCA-IgA-positive healthy donorsor the NPC patients.
Precautions
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Disclaimer
While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.
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