Product Name
Junctophilin-3 (Jph3), Recombinant Protein
Full Product Name
Recombinant Mouse Junctophilin-3 (Jph3), partial
Product Gene Name
Jph3 recombinant protein
[Similar Products]
Product Synonym Gene Name
Jph3[Similar Products]
Research Use Only
For Research Use Only. Not for use in diagnostic procedures.
Sequence
MSSGGRFNFD DGGSYCGGWE DGKAHGHGVC TGPKGQGEYT GSWSHGFEVL GVYTWPSGNT YQGTWAQGKR HGIGLESKGK WVYKGEWTHG FKGRYGVREC TGNGAKYEGT WSNGLQDGYG TETYSDGGTY QGQWVGGMRQ GYGVRQSVPY GMAAVIRSPL RTSINSLRSE HTNGAALHPD ASPAVAGSPA VSRGGFVLVA HSDSEILKSK KKGLFRRSLL SGLKLRKSES KSSLASQRSK QSSFRSEAGM STVSSTASDI HSTISLGEAE AELAVIEDDI DATTTETYVG EWKNDKRSGF GVSQRSDGLK YEGEWVSNRR HGYGCMTFPD GTKEEGKYKQ NVLVSGKRKN LIPLRASKIR EKVDRAVEAA ERAATIAKQK AEIAASRTSH SRAKAEAALT AAQKAQEEAR IARITAKEFS PSFQHRENGL EYQRPKHQMS CDDIEVLSTG TPLQQESPEL YRKGTTPSDL TPDDSPLQSF PASPTSTPPP APASRTKMAH FSRQVSVDEE RSGDIQMLLE GRGGDYARNS WGEEKAGASR GIRSGALRSG QPTEDFRTRG SGHKQPGNPK PRERRTESPT TFSWTSHHRA GNPCSGGPKL LEPDEEQLSN YKLEMKPLLR MDACPQDTHP QRRRHSRGAG GDRGFGLQRL RSKSQNKENL RPASSAEPTV QKLESLRLGD RPEPRLLRWD LTFSPPQKSL PVALESDEET GDELKSSTGS API
3D Structure
ModBase 3D Structure for Q9ET77
Host
E Coli or Yeast or Baculovirus or Mammalian Cell
Purity/Purification
>85% (SDS-PAGE) (lot specific)
Form/Format
Liquid containing glycerol
Tag Information
This protein contains an N-terminal tag and may also contain a C-terminal tag. Tag types are determined by various factors including tag-protein stability, please inquire for tag information.
Sterility
Sterile filter available upon request.
Endotoxin
Low endotoxin available upon request.
Storage Buffer
Tris-based buffer, 50% glycerol
Preparation and Storage
Store at -20 degrees C. For long-term storage, store at -20 degrees C or -80 degrees C. Store working aliquots at 4 degrees C for up to one week. Repeated freezing and thawing is not recommended.
ISO Certification
Manufactured in an ISO 13485:2003 and EN ISO 13485:2012 Certified Laboratory.
Other Notes
Small volumes of Jph3 recombinant protein vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
Related Product Information for
Jph3 recombinant protein
Junctional complexes between the plasma membrane and endoplasmic
sarcoplasmic reticulum are a common feature of all excitable cell types and mediate cross talk between cell surface and intracellular ion channels. This protein is a component of junctional complexes and is composed of a C-terminal hydrophobic segment spanning the endoplasmic
sarcoplasmic reticulum membrane and a remaining cytoplasmic domain that shows specific affinity for the plasma membrane. CAG
CTG repeat expansions at the Huntington s disease (HD)-like 2 locus have been identified in this gene, which is a member of the junctophilin gene family.
NCBI/Uniprot data below describe general gene information for Jph3. It may not necessarily be applicable to this product.
NCBI Accession #
NP_065630.1
[Other Products]
NCBI GenBank Nucleotide #
NM_020605.3
[Other Products]
UniProt Primary Accession #
Q9ET77
[Other Products]
UniProt Secondary Accession #
Q3ZAS3; Q8BNM7; Q9EQZ2[Other Products]
UniProt Related Accession #
Q9ET77[Other Products]
Molecular Weight
81,229 Da
NCBI Official Full Name
junctophilin-3
NCBI Official Synonym Full Names
junctophilin 3
NCBI Official Symbol
Jph3??[Similar Products]
NCBI Official Synonym Symbols
Jp3; JP-3
??[Similar Products]
NCBI Protein Information
junctophilin-3
UniProt Protein Name
Junctophilin-3
UniProt Synonym Protein Names
Junctophilin type 3
Protein Family
Junctophilin
UniProt Gene Name
Jph3??[Similar Products]
UniProt Synonym Gene Names
Jp3; JP-3??[Similar Products]
UniProt Comments for Jph3
Junctophilins contribute to the formation of junctional membrane complexes (JMCs) which link the plasma membrane with the endoplasmic or sarcoplasmic reticulum in excitable cells. Provides a structural foundation for functional cross-talk between the cell surface and intracellular calcium release channels. JPH3 is brain-specific and appears to have an active role in certain neurons involved in motor coordination and memory.
Research Articles on Jph3
1. The expression of JPH isoforms was examined in human and mouse pancreatic tissues, and JPH3 expression was found in both the beta cells.
Precautions
All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
Disclaimer
While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.
It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
