Product Name
Tumor necrosis factor receptor superfamily member EDAR (Edar), Recombinant Protein
Full Product Name
Recombinant Mouse Tumor necrosis factor receptor superfamily member EDAR (Edar), partial
Product Gene Name
Edar recombinant protein
[Similar Products]
Product Synonym Gene Name
Edar[Similar Products]
Research Use Only
For Research Use Only. Not for use in diagnostic procedures.
Sequence Positions
27-187
Sequence
EDSN CGENEYHNQT TGLCQQCPPC RPGEEPYMSC GYGTKDDDYG CVPCPAEKFS KGGYQICRRH KDCEGFFRAT VLTPGDMEND AECGPCLPGY YMLENRPRNI YGMVCYSCLL APPNTKECVG ATSGVSAHSS STSGGSTLSP FQHAHKELSG QGHLATA
3D Structure
ModBase 3D Structure for Q9R187
Host
E Coli or Yeast or Baculovirus or Mammalian Cell
Purity/Purification
>85% (SDS-PAGE) (lot specific)
Form/Format
Liquid containing glycerol
Tag Information
This protein contains an N-terminal tag and may also contain a C-terminal tag. Tag types are determined by various factors including tag-protein stability, please inquire for tag information.
Sterility
Sterile filter available upon request.
Endotoxin
Low endotoxin available upon request.
Storage Buffer
Tris-based buffer, 50% glycerol
Preparation and Storage
Store at -20 degrees C. For long-term storage, store at -20 degrees C or -80 degrees C. Store working aliquots at 4 degrees C for up to one week. Repeated freezing and thawing is not recommended.
ISO Certification
Manufactured in an ISO 13485:2003 and EN ISO 13485:2012 Certified Laboratory.
Other Notes
Small volumes of Edar recombinant protein vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
Related Product Information for
Edar recombinant protein
This gene encodes a member of the tumor necrosis factor receptor family. The encoded transmembrane protein is a receptor for the soluble ligand ectodysplasin A, and can activate the nuclear factor-kappaB, JNK, and caspase-independent cell death pathways. It is required for the development of hair, teeth, and other ectodermal derivatives. Mutations in this gene result in autosomal dominant and recessive forms of hypohidrotic ectodermal dysplasia.
NCBI/Uniprot data below describe general gene information for Edar. It may not necessarily be applicable to this product.
NCBI Accession #
NP_034230.1
[Other Products]
NCBI GenBank Nucleotide #
NM_010100.3
[Other Products]
UniProt Primary Accession #
Q9R187
[Other Products]
UniProt Secondary Accession #
Q9DC43[Other Products]
UniProt Related Accession #
Q9R187[Other Products]
Molecular Weight
48,434 Da
NCBI Official Full Name
tumor necrosis factor receptor superfamily member EDAR
NCBI Official Synonym Full Names
ectodysplasin-A receptor
NCBI Official Symbol
Edar??[Similar Products]
NCBI Official Synonym Symbols
dl; ED3; ED5; ED1R; EDA3; EDA-A1R
??[Similar Products]
NCBI Protein Information
tumor necrosis factor receptor superfamily member EDAR
UniProt Protein Name
Tumor necrosis factor receptor superfamily member EDAR
UniProt Synonym Protein Names
Anhidrotic ectodysplasin receptor 1; Downless; Ectodermal dysplasia receptor; Ectodysplasin-A receptor
Protein Family
Tumor necrosis factor receptor superfamily
UniProt Gene Name
Edar??[Similar Products]
UniProt Synonym Gene Names
Dl??[Similar Products]
UniProt Comments for Edar
Receptor for EDA isoform TAA, but not for EDA isoform TA-2 (). May mediate the activation of NF-kappa-B and JNK. May promote caspase-independent cell death.
Research Articles on Edar
1. EDAR protein signaling pathway plays an important role in wound healing in mice and human.
Precautions
All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
Disclaimer
While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.
It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.