Product Name
Rab27a, Blocking Peptide
Full Product Name
Rab27a Peptide - middle region
Product Gene Name
Rab27a blocking peptide
[Similar Products]
Product Synonym Gene Name
2210402C08Rik; 2410003M20Rik; 4933437C11Rik; ash[Similar Products]
Rab27a peptide (MBS3237800) is used for blocking the activity of Rab27a antibody (MBS3212854)
Research Use Only
For Research Use Only. Not for use in diagnostic procedures.
Sequence
DAMGFLLLFD LTNEQSFLNV RNWISQLQMH AYCENPDIVL CGNKSDLEDQ
3D Structure
ModBase 3D Structure for Q9ERI2
Species Reactivity
Mouse, Human
Form/Format
Lyophilized powder
Preparation and Storage
Add 100ul of sterile PBS. Final peptide concentration is 1 mg/ml in PBS. For longer periods of storage, store at -20 degree C. Avoid repeat freeze-thaw cycles.
Other Notes
Small volumes of Rab27a blocking peptide vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
Related Product Information for
Rab27a blocking peptide
This is a synthetic peptide designed for use in combination with anti-Rab27a Antibody, made
Target Description: Rab27a plays a role in cytotoxic granule exocytosis in lymphocytes. It is required for both granule maturation and granule docking and priming at the immunologic synapse.
Product Categories/Family for Rab27a blocking peptide
Peptide
Applications Tested/Suitable for Rab27a blocking peptide
Western Blot (WB)
NCBI/Uniprot data below describe general gene information for Rab27a. It may not necessarily be applicable to this product.
NCBI Accession #
NP_076124
[Other Products]
NCBI GenBank Nucleotide #
NM_023635
[Other Products]
UniProt Primary Accession #
Q9ERI2
[Other Products]
UniProt Related Accession #
Q9ERI2[Other Products]
NCBI Official Full Name
ras-related protein Rab-27A
NCBI Official Synonym Full Names
RAB27A, member RAS oncogene family
NCBI Official Symbol
Rab27a??[Similar Products]
NCBI Official Synonym Symbols
ash; 2210402C08Rik; 2410003M20Rik; 4933437C11Rik
??[Similar Products]
NCBI Protein Information
ras-related protein Rab-27A
UniProt Protein Name
Ras-related protein Rab-27A
Protein Family
Ras-related protein
UniProt Gene Name
Rab27a??[Similar Products]
UniProt Entry Name
RB27A_MOUSE
NCBI Summary for Rab27a
The protein encoded by this gene is a member of the Rab family of proteins, which is the largest family within the Ras superfamily of GTPases. This gene product is thought to regulate vesicular transport, together with its specific effectors. Mutations in this gene cause several defects, including actin-based melanosome transport defects and immunodeficiency. Mutations in the human ortholog of this gene are associated with Griscelli syndrome type 2. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jul 2014]
Research Articles on Rab27a
1. IRF-1 regulates Rab27a transcription and extracellular vesicles secretion, leading to oxidized phospholipids activation of neutrophils and subsequent hepatic ischemia reperfusion injury
Precautions
All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
Disclaimer
While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.
It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
