EIF1AX; EIF1A; EIF1AP1; EIF4C; eIF-1A; eIF-4C; eukaryotic translation initiation factor 1A, X-linked

For Research Use Only. Not for use in diagnostic procedures.

Polyclonal

IgG

Affinity Purification

Store at -20°C
Avoid freeze / thaw cycles.

Small volumes of anti-EIF1AX antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

This gene encodes an essential eukaryotic translation initiation factor. The protein is required for the binding of the 43S complex (a 40S subunit, eIF2/GTP/Met-tRNAi and eIF3) to the 5' end of capped RNA

Polyclonal

Western Blot (WB), Immunohistochemistry (IHC)

WB: 1:200 - 1:2000
IHC: 1:100 - 1:200

Western blot analysis of extracts of various cell lines, using EIF1AX antibody at 1:1000 dilution.
Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (MBS128200) at 1:10000 dilution.
Lysates/proteins: 25ug per lane.
Blocking buffer: 3% nonfat dry milk in TBST.
Detection: ECL Basic Kit.
Exposure time: 30s.

Immunohistochemistry of paraffin-embedded human stomach using EIF1AX antibody at dilution of 1:100 (40x lens).

Immunohistochemistry of paraffin-embedded mouse brain using EIF1AX antibody at dilution of 1:100 (40x lens).

Calculated: 16kDa
Observed: 16kDa

eukaryotic translation initiation factor 1A, X-linked

eukaryotic translation initiation factor 1A, X-chromosomal; eIF-1A X isoform; eukaryotic translation initiation factor 4C; Putative eukaryotic translation initiation factor 1A; eukaryotic translation initiation factor 1A, X chromosome

Eukaryotic translation initiation factor 1A, X-chromosomal

EIF1A; EIF4C; eIF-1A X isoform; eIF-4C??[Similar Products]

IF1AX_HUMAN

This gene encodes an essential eukaryotic translation initiation factor. The protein is required for the binding of the 43S complex (a 40S subunit, eIF2/GTP/Met-tRNAi and eIF3) to the 5' end of capped RNA. [provided by RefSeq, Jul 2008]

EIF1AX: Seems to be required for maximal rate of protein biosynthesis. Enhances ribosome dissociation into subunits and stabilizes the binding of the initiator Met-tRNA(I) to 40 S ribosomal subunits. Belongs to the eIF-1A family

Protein type: Translation initiation; RNA-binding; Translation

Chromosomal Location of Human Ortholog: Xp22.12

Cellular Component: cytosol

Molecular Function: protein binding; translation factor activity, nucleic acid binding; translation initiation factor activity

Biological Process: cellular protein metabolic process; translation; translational initiation; gene expression

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