2-5-Oligoisoadenylate Synthetase 1 (OAS1) Antibody
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產(chǎn)品名稱: 2-5-Oligoisoadenylate Synthetase 1 (OAS1) Antibody
產(chǎn)品型號: abx001970
產(chǎn)品展商: 其他品牌
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簡單介紹
2-5-Oligoisoadenylate Synthetase 1 (OAS1) Antibody
2-5-Oligoisoadenylate Synthetase 1 (OAS1) Antibody
的詳細介紹
OAS1 Antibody is a Rabbit Polyclonal antibody against OAS1. This gene encodes a member of the 2-5A synthetase family, essential proteins involved in the innate immune response to viral infection. The encoded protein is induced by interferons and uses adenosine triphosphate in 2'-specific nucleotidyl transfer reactions to synthesize 2',5'-oligoadenylates (2-5As). These molecules activate latent RNase L, which results in viral RNA degradation and the inhibition of viral replication. The three known members of this gene family are located in a cluster on chromosome 12. Mutations in this gene have been associated with host susceptibility to viral infection. Alternatively spliced transcript variants encoding different isoforms have been described.
| Target |
2-5-Oligoisoadenylate Synthetase 1 (OAS1) |
| Reactivity |
Human, Mouse |
| Host |
Rabbit |
| Clonality |
Polyclonal |
| Tested Applications |
WB, IF/ICC |
| Recommended dilutions |
WB: 1/500 - 1/2000, IF/ICC: 1/50 - 1/100. Optimal dilutions/concentrations should be determined by the end user. |
| Immunogen |
Recombinant protein of human OAS1. |
| Purification |
Affinity purified. |
| Form |
Liquid |
| Isotype |
IgG |
| Conjugation |
Unconjugated |
| Storage |
Aliquot and store at -20 °C. Avoid repeated freeze/thaw cycles. |
| Molecular Weight |
Calculated MW: 41 kDa/43 kDa/46 kDa/47 kDa
Observed MW: 40 kDa |
| Swiss Prot |
P00973
|
| GeneID |
4938
|
| Gene Symbol |
OAS1 |
| Concentration |
> 1 mg/ml |
| Buffer |
PBS, pH 7.3, 0.02% sodium azide, 50% glycerol. |
| UNSPSC Code |
12352203 |
| Availability |
Shipped within 5-10 working days. |
| Note |
This product is for research use only. |
