Acyl-CoA Synthetase Long-Chain Family Member 5 (ACSL5) Antibody
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產(chǎn)品名稱: Acyl-CoA Synthetase Long-Chain Family Member 5 (ACSL5) Antibody
產(chǎn)品型號(hào): abx001175
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Acyl-CoA Synthetase Long-Chain Family Member 5 (ACSL5) Antibody
Acyl-CoA Synthetase Long-Chain Family Member 5 (ACSL5) Antibody
的詳細(xì)介紹
ACSL5 Antibody is a Rabbit Polyclonal antibody against ACSL5. Acyl-CoA synthetase 5, a member of the ACSL gene family that catalyzes the activation of long-chain fatty acids for lipid biosynthesis, is the only ACSL isoform that is both, located on mitochondria and functionally involved in enterocyte apoptosis.ACSL5 could play a role in promoting fatty acid-induced lipoapoptosis in hepatocytes as important mechanism in fatty liver-related disorders(PMID:20470896). ACSL5 is most abundant in liver, brown adipose tissue, and intestine and is located on both the mitochondrial membrane and endoplasmic reticulum(PMID:20798351). It has 3 isoforms produced by alternative splicing. This antibody is specific to ACSL5.
| Target |
ACSL5 |
| Reactivity |
Human, Mouse, Rat |
| Host |
Rabbit |
| Clonality |
Polyclonal |
| Tested Applications |
WB, IHC |
| Recommended dilutions |
WB: 1/500 - 1/2000, IHC: 1/20 - 1/100. Optimal dilutions/concentrations should be determined by the end user. |
| Immunogen |
Recombinant protein of human ACSL5. |
| Purification |
Affinity purified. |
| Form |
Liquid |
| Isotype |
IgG |
| Conjugation |
Unconjugated |
| Storage |
Aliquot and store at -20 °C. Avoid repeated freeze/thaw cycles. |
| Molecular Weight |
Calculated MW: 73 kDa/75 kDa/82 kDa Observed MW: 76 kDa |
| Swiss Prot |
Q9ULC5
|
| GeneID |
51703
|
| Gene Symbol |
ACSL5 |
| Concentration |
> 1 mg/ml |
| Buffer |
PBS, pH 7.3, 0.02% sodium azide, 50% glycerol. |
| UNSPSC Code |
12352203 |
| Availability |
Shipped within 5-10 working days. |
| Note |
This product is for research use only. |