Agouti Signaling Protein (ASIP) Antibody
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產(chǎn)品名稱: Agouti Signaling Protein (ASIP) Antibody
產(chǎn)品型號: abx005235
產(chǎn)品展商: 其他品牌
產(chǎn)品文檔: 無相關文檔
簡單介紹
Agouti Signaling Protein (ASIP) Antibody
Agouti Signaling Protein (ASIP) Antibody
的詳細介紹
ASIP Antibody is a Rabbit Polyclonal antibody against ASIP. In mice, the agouti gene encodes a paracrine signaling molecule that causes hair follicle melanocytes to synthesize pheomelanin, a yellow pigment, instead of the black or brown pigment, eumelanin. Pleiotropic effects of constitutive expression of the mouse gene include *****-onset obesity, increased tumor susceptibility, and premature infertility. This gene is highly similar to the mouse gene and encodes a secreted protein that may affect the quality of hair pigmentation, act as a pharmacological antagonist of alpha-melanocyte-stimulating hormone, play a role in neuroendocrine aspects of melanocortin action, and have a functional role in regulating lipid metabolism in adipocytes.
| Target |
ASIP |
| Reactivity |
Human, Mouse |
| Host |
Rabbit |
| Clonality |
Polyclonal |
| Tested Applications |
IHC |
| Recommended dilutions |
IHC: 1/50 - 1/100. Optimal dilutions/concentrations should be determined by the end user. |
| Immunogen |
Recombinant protein of human ASIP. |
| Purification |
Affinity purified. |
| Form |
Liquid |
| Isotype |
IgG |
| Conjugation |
Unconjugated |
| Storage |
Aliquot and store at -20 °C. Avoid repeated freeze/thaw cycles. |
| Molecular Weight |
Calculated MW: 14 kDa |
| Swiss Prot |
P42127
|
| GeneID |
434
|
| Gene Symbol |
ASIP |
| Concentration |
> 1 mg/ml |
| Buffer |
PBS, pH 7.3, 0.02% sodium azide, 50% glycerol. |
| UNSPSC Code |
12352203 |
| Availability |
Shipped within 5-10 working days. |
| Note |
This product is for research use only. |