Aldehyde Dehydrogenase, Mitochondrial (ALDH2) Antibody
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產(chǎn)品名稱: Aldehyde Dehydrogenase, Mitochondrial (ALDH2) Antibody
產(chǎn)品型號: abx025191
產(chǎn)品展商: 其他品牌
產(chǎn)品文檔: 無相關(guān)文檔
簡單介紹
Aldehyde Dehydrogenase, Mitochondrial (ALDH2) Antibody
Aldehyde Dehydrogenase, Mitochondrial (ALDH2) Antibody
的詳細介紹
This protein belongs to the aldehyde dehydrogenase family of proteins. Aldehyde dehydrogenase is the second enzyme of the major oxidative pathway of alcohol metabolism. Two major liver isoforms of this enzyme, cytosolic and mitochondrial, can be distinguished by their electrophoretic mobilities, kinetic properties, and subcellular localizations. Most Caucasians have two major isozymes, while approximately 50% of Orientals have only the cytosolic isozyme, missing the mitochondrial isozyme. A remarkably higher frequency of acute alcohol intoxication among Orientals than among Caucasians could be related to the absence of the mitochondrial isozyme. This gene encodes a mitochondrial isoform, which has a low Km for acetaldehydes, and is localized in mitochondrial matrix.
| Target |
ALDH2 |
| Reactivity |
Human |
| Host |
Mouse |
| Clonality |
Monoclonal |
| Tested Applications |
WB, IHC, IF/ICC, FCM |
| Recommended dilutions |
Optimal dilutions/concentrations should be determined by the end user. |
| Immunogen |
Human ALDH2. |
| Purification |
Purified Mouse Monoclonal Antibody. |
| Isotype |
IgG1κ |
| Conjugation |
Unconjugated |
| Specificity |
This ALDH2 Monoclonal antibody is generated from mouse immunized with ALDH2 recombinant protein. |
| Storage |
Aliquot and store at -20 °C. Avoid repeated freeze/thaw cycles. |
| Swiss Prot |
P05091
|
| Buffer |
PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein G column, eluted with high and low pH buffers and neutralized immediately, followed by dialysis against PBS. |
| UNSPSC Code |
12352203 |
| Availability |
Shipped within 5-10 working days. |
| Note |
This product is for research use only. |
