Alkaline Phosphatase, Placental Type (ALPP) Antibody
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產(chǎn)品名稱: Alkaline Phosphatase, Placental Type (ALPP) Antibody
產(chǎn)品型號(hào): abx001287
產(chǎn)品展商: 其他品牌
產(chǎn)品文檔: 無相關(guān)文檔
簡單介紹
Alkaline Phosphatase, Placental Type (ALPP) Antibody
Alkaline Phosphatase, Placental Type (ALPP) Antibody
的詳細(xì)介紹
ALPP Antibody is a Rabbit Polyclonal antibody against ALPP. Alkaline phosphatases (AP) are glycosyl-phosphatidylinositol (GPI)-anchored, dimeric, Zn2+-metallated glycoproteins that catalyze the hydrolysis of phosphomonoesters into an inorganic phosphate and an alcohol. Placental alkaline phosphatase (also known as PLAP, ALPP, PALP, placental ALP-1 or Regan isozyme) is a 530 amino acid, tissue-specific AP that is expressed in the placenta, the serum of pregnant women and ectopically expressed in various cancers, including those of the ovary and testis. PLAP may assist in guiding migratory cells and transporting specific molecules, such as fatty acids and immunoglobulins, across the plasma membrane. The three tissue-specific APs identified in human, PLAP, germ cell AP (GCAP) and intestinal AP, are 90-98% homologous and their genes are clustered on chromosome 2q.
| Target |
ALPP |
| Reactivity |
Human |
| Host |
Rabbit |
| Clonality |
Polyclonal |
| Tested Applications |
WB, IHC |
| Recommended dilutions |
WB: 1/500 - 1/1000, IHC: 1/50 - 1/100. Optimal dilutions/concentrations should be determined by the end user. |
| Immunogen |
Recombinant fusion protein of human ALPP. |
| Purification |
Affinity purified. |
| Form |
Liquid |
| Isotype |
IgG |
| Conjugation |
Unconjugated |
| Storage |
Store at 4 °C. |
| Molecular Weight |
Calculated MW: 57 kDa
Observed MW: 58 kDa |
| Swiss Prot |
P05187
|
| GeneID |
250
|
| Gene Symbol |
ALPP |
| Concentration |
> 1 mg/ml |
| Buffer |
PBS, pH 7.3, 0.02% sodium azide. |
| UNSPSC Code |
12352203 |
| Availability |
Shipped within 5-10 working days. |
| Note |
This product is for research use only. |
