Alpha Actinin 4 (ACTN4) Antibody
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產(chǎn)品名稱: Alpha Actinin 4 (ACTN4) Antibody
產(chǎn)品型號(hào): abx002333
產(chǎn)品展商: 其他品牌
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簡(jiǎn)單介紹
Alpha Actinin 4 (ACTN4) Antibody
的詳細(xì)介紹
ACTN4 Antibody is a Rabbit Polyclonal antibody against ACTN4. Alpha actinins belong to the spectrin gene superfamily which represents a diverse group of cytoskeletal proteins, including the alpha and beta spectrins and dystrophins. Alpha actinin is an actin-binding protein with multiple roles in different cell types. In nonmuscle cells, the cytoskeletal isoform is found along microfilament bundles and adherens-type junctions, where it is involved in binding actin to the membrane. In contrast, skeletal, cardiac, and smooth muscle isoforms are localized to the Z-disc and analogous dense bodies, where they help anchor the myofibrillar actin filaments. This gene encodes a nonmuscle, alpha actinin isoform which is concentrated in the cytoplasm, and thought to be involved in metastatic processes. Mutations in this gene have been associated with focal and segmental glomerulosclerosis.
| Target |
ACTN4 |
| Reactivity |
Human |
| Host |
Rabbit |
| Clonality |
Polyclonal |
| Tested Applications |
WB, IHC, FCM |
| Recommended dilutions |
WB: 1/500 - 1/2000, IHC: 1/50 - 1/100, FCM: 1/20 - 1/50. Optimal dilutions/concentrations should be determined by the end user. |
| Immunogen |
Recombinant protein of human ACTN4. |
| Purification |
Affinity purified. |
| Form |
Liquid |
| Isotype |
IgG |
| Conjugation |
Unconjugated |
| Storage |
Store at 4 °C. |
| Molecular Weight |
Calculated MW: 59 kDa/79 kDa/104 kDa
Observed MW: 105 kDa |
| Swiss Prot |
O43707
|
| GeneID |
81
|
| Gene Symbol |
ACTN4 |
| Concentration |
> 1 mg/ml |
| Buffer |
PBS, pH 7.3, 0.02% sodium azide. |
| UNSPSC Code |
12352203 |
| Availability |
Shipped within 5-10 working days. |
| Note |
This product is for research use only. |
