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產(chǎn)品名稱: Alsin (ALS2) Antibody
產(chǎn)品型號(hào): abx032830
產(chǎn)品展商: 其他品牌
產(chǎn)品文檔: 無(wú)相關(guān)文檔
簡(jiǎn)單介紹
Alsin (ALS2) Antibody
的詳細(xì)介紹
ALS2 contains an ATS1/RCC1-like domain, a RhoGEF domain, and a vacuolar protein sorting 9 (VPS9) domain, all of which are guanine-nucleotide exchange factors that activate members of the Ras superfamily of GTPases. The protein functions as a guanine nucleotide exchange factor for the small GTPase RAB5. The protein localizes with RAB5 on early endosomal compartments, and functions as a modulator for endosomal dynamics. Mutations in its gene result in several forms of juvenile lateral sclerosis and infantile-onset ascending spastic paralysis.
| Target |
ALS2 |
| Reactivity |
Human, Mouse |
| Host |
Rabbit |
| Clonality |
Polyclonal |
| Tested Applications |
WB, IHC |
| Recommended dilutions |
Optimal dilutions/concentrations should be determined by the end user. |
| Immunogen |
Human ALS2. |
| Purification |
Purified Rabbit Polyclonal Antibody. |
| Isotype |
IgG |
| Conjugation |
Unconjugated |
| Specificity |
This ALS2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 1248-1277 amino acids from the C-terminal region of human ALS2. |
| Storage |
Aliquot and store at -20 °C. Avoid repeated freeze/thaw cycles. |
| Swiss Prot |
Q96Q42
|
| Buffer |
PBS with 0.09% (W/V) sodium azide. This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS. |
| UNSPSC Code |
12352203 |
| Availability |
Shipped within 5-10 working days. |
| Note |
This product is for research use only. |
