Caspase 8 (pS347) Antibody
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產(chǎn)品名稱: Caspase 8 (pS347) Antibody
產(chǎn)品型號: abx012070
產(chǎn)品展商: 其他品牌
產(chǎn)品文檔: 無相關(guān)文檔
簡單介紹
Caspase 8 (pS347) Antibody
的詳細介紹
Phospho-Caspase 8 (Ser347) Antibody detects endogenous levels of Caspase 8 only when phosphorylated at Serine 347. This gene encodes a protein that is a member of the cysteine-aspartic acid protease (caspase) family. Sequential activation of caspases plays a central role in the execution-phase of cell apoptosis. Caspases exist as inactive proenzymes composed of a prodomain, a large protease subunit, and a small protease subunit. Activation of caspases requires proteolytic processing at conserved internal aspartic residues to generate a heterodimeric enzyme consisting of the large and small subunits.
| Target |
Caspase 8 (pS347) |
| Reactivity |
Human, Rat |
| Host |
Rabbit |
| Clonality |
Polyclonal |
| Tested Applications |
WB |
| Recommended dilutions |
Optimal dilutions/concentrations should be determined by the end user. |
| Purification |
Purified by affinity chromatography. |
| Conjugation |
Unconjugated |
| Storage |
Aliquot and store at -20 °C. Avoid repeated freeze/thaw cycles. |
| Swiss Prot |
Q14790
|
| GeneID |
841
|
| Gene Symbol |
CASP8 |
| OMIM |
601763
|
| Enzyme Commission Number |
EC 3.4.22.-, EC 3.4.22.61 |
| HGNC |
1509 |
| Ensembl |
ENSG00000064012 |
| Buffer |
PBS, pH 7.4, 150 mM NaCl, 0.02% sodium azide and 50% glycerol. |
| UNSPSC Code |
12352203 |
| Availability |
Shipped within 5-10 working days. |
| Note |
This product is for research use only. |
