μ-conotoxin-PIIIA
Blocker of Nav1.4 channels
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產(chǎn)品名稱: μ-conotoxin-PIIIA
Blocker of Nav1.4 channels
產(chǎn)品型號: 08CON006-00100
產(chǎn)品展商: 其他品牌
產(chǎn)品文檔: 無相關(guān)文檔
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μ-conotoxin-PIIIA
Blocker of Nav1.4 channels
的詳細(xì)介紹
μ-conotoxin-PIIIA
Blocker of Nav1.4 channels
μ-Conotoxin PIIIA (mu-conotoxin PIIIA) is a conotoxin that has been isolated from the venom of the cone Conus purpurascens. μ-conotoxin PIIIA demonstrates a higher affinity for the mammalian muscle sodium channel Nav1.4 (IC50 ~ 44 nM) than for the CNS Nav1.2 subtype (IC50 ~ 640 nm). μ-Conotoxin PIIIA blocks more irreversibly amphibian muscle sodium channels than mammalian ones.