Cy3-Crotamine
Fluorescent tumor-cell specific agent
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產(chǎn)品名稱: Cy3-Crotamine
Fluorescent tumor-cell specific agent
產(chǎn)品型號: CRO002
產(chǎn)品展商: 其他品牌
產(chǎn)品文檔: 無相關(guān)文檔
簡單介紹
Cy3-Crotamine
Fluorescent tumor-cell specific agent
的詳細介紹
Cy3-Crotamine
Fluorescent tumor-cell specific agent
Crotamine is a basic peptide present in the venom of the South American rattlesnake Crotalus durissus terrificus. Multiple biological functions have been attributed to Crotamine. It is a natural cell-penetrating peptide with selective biological action towards actively proliferating cell types such as tumor cells. Moreover, it has been reported that crotamine is a blocker of Kv1.3 (IC50 around 300 nM) as well as Kv1.1 and Kv1.2. It has analgesic properties and myonecrotic effects. In addition, crotamine belongs to the beta-defensin peptides and as such demonstrates antibacterial properties by interacting with lipid membranes.
Cy3-crotamine is a fluorescent version of Crotamine.
