Huwentoxin-XVI
Huwentoxin-XVI is a selective blocker of N-type Ca2+ channels
如果您對該產(chǎn)品感興趣的話,可以
產(chǎn)品名稱: Huwentoxin-XVI
Huwentoxin-XVI is a selective blocker of N-type Ca2+ channels
產(chǎn)品型號:
產(chǎn)品展商: 其他品牌
產(chǎn)品文檔: 無相關(guān)文檔
簡單介紹
Huwentoxin-XVI
Huwentoxin-XVI is a selective blocker of N-type Ca2+ channels
的詳細(xì)介紹
Huwentoxin-XVI
Huwentoxin-XVI is a selective blocker of N-type Ca2+ channels
Huwentoxin-XVI is a 39 amino acids peptide that was discovered from the venom of the Chinese tarantula Ornithoctonus huwena. Huwentoxin-XVI was shown to be a potent blocker of HVA N-type calcium channels with an IC50 value of 60 nM in rat DRG. The blocking effect appears to be similar to that of ω-conotoxin-GVIA and ω-conotoxin-MVIIA. Neverthelss, Huwentoxin-XVI differs from GVIA and MVIIA thanks to its greater reversibility and its higher selectivity for N-type over P/Q type than MVIIA.
