Iberiotoxin
Blocker of high conductance Ca2+-activated K+ channel
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產品名稱: Iberiotoxin
Blocker of high conductance Ca2+-activated K+ channel
產品型號: 12IBX001-50010
產品展商: 其他品牌
產品文檔: 無相關文檔
簡單介紹
Iberiotoxin
Blocker of high conductance Ca2+-activated K+ channel
的詳細介紹
Iberiotoxin
Blocker of high conductance Ca2+-activated K+ channel
Iberiotoxin (IbTx) is a toxin that was originally isolated from Buthus tamulus scorpion venom. Iberiotoxin inhibits selectively the high conductance Ca2+-activated K+ channel (KCa1.1) at nanomolar concentrations (IC50 ~2 nM). This toxin does not affect other types of calcium-dependent or voltage-dependent K+ channels. Iberiotoxin is a valuable tool to study specifically Maxi-K channels.